An interventional fiber optic strategy, as a representative optical medical technology, is flexible, highly sensitive, minimally invasive, and anti-electromagnetic and has good biosafety. Fiber

An interventional fiber optic strategy, as a representative optical medical technology, is flexible, highly sensitive, minimally invasive, and anti-electromagnetic and has good biosafety. Fiber optics can approach deep cancer lesions and provide direct theranostics, which other optical technologies cannot achieve. However, the realization of cancer sensing and therapy relies on the functionalization of optical fibers, which requires the strict selection and optimization of functional materials used to modify the optical fibers, ensuring high photothermal conversion efficiency without affecting fluorescence detection efficiency. Herein, we propose the use of black phosphorus, which does not interfere with fluorescence and provides a safer and more efficient photothermal effect compared to other nanomaterials, such as graphene, graphene oxide, carbon nanotubes, and MXene. We developed a fiber-optic theranostic probe that combines nitroreductase (NTR) fluorescent molecules and a black phosphorus/gold nanostar (BP/AuNS) nanomaterial hydrogel to develop an integrated strategy for cancer sensing and photothermal therapy (PTT). The sensor has high sensitivity, and the limit of detection (LOD) is 1.61 ng mL-1. BP/AuNS fibers have excellent photothermal effects, and the probe temperature reached 212°C in air as 150 mW of pump power was delivered. In the phantom test, the simulation and test results showed that the fiber probe conferred hyperthermia (>45°C) to an area with a radius of 2.5 mm. These results indicate that the minimally invasive BP/AuNS fiber exhibits excellent sensing performance and high photothermal efficiency, making it promising for tumor diagnosis and treatment and potentially advancing the development of optical fiber medicine.show less

Nonlinear compression experiments based on multiple solid thin plates are conducted in an ultra-high peak power Ti:Sapphire laser system. The incident laser pulse, with an energy of 80 mJ and a

Nonlinear compression experiments based on multiple solid thin plates are conducted in an ultra-high peak power Ti:Sapphire laser system. The incident laser pulse, with an energy of 80 mJ and a pulse width of 30.2 fs is compressed to 10.1 fs by a thin-plate based nonlinear compression. Significant small-scale self-focusing (SSSF) is observed as ring structures appears in the near-field of the output pulse at high energy. Numerical simulations based on the experimental setup provide a good explanation for the observed phenomena, offering quantitative predictions of the spectrum, pulse width, dispersion, and near- and far-field distributions of the compressed laser pulse.show less

Low-density polymer foams pre-ionized by a well-controlled nanosecond pulse are excellent plasma targets to trigger direct laser acceleration (DLA) of electrons by sub-picosecond relativistic la

Low-density polymer foams pre-ionized by a well-controlled nanosecond pulse are excellent plasma targets to trigger direct laser acceleration (DLA) of electrons by sub-picosecond relativistic laser pulse. In this work, the influence of the ns pulse on DLA process is investigated. The density profile of plasma generated after irradiating foam with ns pulse was simulated with a two-dimensional hydrodynamic code, which takes into account the high aspect ratio of interaction and the microstructure of polymer foams. The obtained plasma density profile was used as input to the 3D PIC code to simulate energy, angular distributions and charge carried by the directional fraction of DLA electrons. The modelling shows good agreement with experiment and in general a weak dependence of the electron spectra on the plasma profiles, which contain density up-ramp and region of near critical electron density. This explains the high DLA stability in pre-ionized foams, which is important for applications.show less

Confronting the escalating global challenge of counterfeit products, developing advanced anticounterfeiting materials and structures with physical unclonable functions (PUFs) becomes imperative.

Confronting the escalating global challenge of counterfeit products, developing advanced anticounterfeiting materials and structures with physical unclonable functions (PUFs) becomes imperative. All-optical PUFs, distinguished by their high output complexity, and expansive response space, offer a promising alternative to conventional electronic counterparts. For practical authentications, the expansion of optical PUF keys usually involves intricate spatial or spectral shaping of excitation light using bulky external apparatus, which largely hinders the applications of optical PUFs. Here, we report a plasmonic PUF system based on heterogeneous nanostructures. The template-assisted shadow deposition technique was employed to adjust the morphological diversity of densely packed metal nanoparticles in individual PUFs. Transmission images were processed via a hash algorithm, and the generated PUF keys with a scalable capacity from 2⁸⁷⁵ to 2⁴³⁴⁰¹ exhibit excellent uniqueness, randomness, and reproducibility. Furthermore, the wavelength and the polarization state of excitation light are harnessed as two distinct expanding strategies, offering the potential for multi-scenario applications via a single PUF. Overall, our reported plasmonic PUFs operated with the multi-dimensional expanding strategy are envisaged to serve as easy-to-integrate, and easy-to-use systems, and promise efficacy across a broad spectrum of applications, from anti-counterfeiting to data encryption and authentication.show less