• Chinese Optics Letters
  • Vol. 20, Issue 1, 011701 (2022)
Mingming Wan1, Shanshan Liang2、**, Xinyu Li3, Zhengyu Duan4, Jiebin Zou1, Jun Chen1、5, Jin Yuan6, and Jun Zhang7、*
Author Affiliations
  • 1School of Electronics and Information Technology, Sun Yat-sen University, Guangzhou 510006, China
  • 2National Innovation Center for Advanced Medical Devices, Shenzhen 518131, China
  • 3GBA Branch of Aerospace Information Research Institute, Chinese Academy of Sciences, Guangzhou 510530, China
  • 4School of Biomedical Engineering, Sun Yat-sen University, Guangzhou 510006, China
  • 5State Key Laboratory of Optoelectronic Materials and Technologies, School of Electronics and Information Technology, Sun Yat-sen University, Guangzhou 510275, China
  • 6State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China
  • 7School of Artificial Intelligence, Guilin University of Electronic Technology, Guilin 541004, China
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    DOI: 10.3788/COL202220.011701 Cite this Article Set citation alerts
    Mingming Wan, Shanshan Liang, Xinyu Li, Zhengyu Duan, Jiebin Zou, Jun Chen, Jin Yuan, Jun Zhang. Dual-beam delay-encoded all fiber Doppler optical coherence tomography for in vivo measurement of retinal blood flow[J]. Chinese Optics Letters, 2022, 20(1): 011701 Copy Citation Text show less

    Abstract

    In this paper, we propose and demonstrate a dual-beam delay-encoded Doppler spectral domain optical coherence tomography (OCT) system for in vivo measurement of absolute retinal blood velocity and flow with arbitrary orientation. The incident beam is split by a beam displacer into two probe beams of the single-spectrometer spectral domain OCT system with orthogonal polarization states and an optical path length delay. We validate our approach with a phantom and in vivo experiments of human retinal blood flow, respectively.
    V=(ϕ2ϕ1)λ04πnτ·cosβ·Δα,

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    F=SVdSdt=SXZV·dSxz·cosβdt=SXZ(ϕ2ϕ1)λ04πnτ·Δαdxdzdt,

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    Mingming Wan, Shanshan Liang, Xinyu Li, Zhengyu Duan, Jiebin Zou, Jun Chen, Jin Yuan, Jun Zhang. Dual-beam delay-encoded all fiber Doppler optical coherence tomography for in vivo measurement of retinal blood flow[J]. Chinese Optics Letters, 2022, 20(1): 011701
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