• Photonics Research
  • Vol. 10, Issue 1, 120 (2022)
Ivy H. M. Wong, Yan Zhang, Zhenghui Chen, Lei Kang, and Terence T. W. Wong*
Author Affiliations
  • Translational and Advanced Bioimaging Laboratory, Department of Chemical and Biological Engineering, Hong Kong University of Science and Technology, Hong Kong, China
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    DOI: 10.1364/PRJ.440935 Cite this Article Set citation alerts
    Ivy H. M. Wong, Yan Zhang, Zhenghui Chen, Lei Kang, Terence T. W. Wong. Slide-free histological imaging by microscopy with ultraviolet surface excitation using speckle illumination[J]. Photonics Research, 2022, 10(1): 120 Copy Citation Text show less
    References

    [1] B. W. Maloney, D. McClatchy, B. Pogue, K. Paulsen, W. Wells, R. Barth. Review of methods for intraoperative margin detection for breast conserving surgery. J. Biomed. Opt., 23, 100901(2018).

    [2] J. B. Taxy. Frozen section and the surgical pathologist a point of view. Arch. Pathol. Lab. Med., 133, 1135-1138(2009).

    [3] F. T. Nguyen, A. M. Zysk, E. J. Chaney, J. G. Kotynek, U. J. Oliphant, F. J. Bellafiore, K. M. Rowland, P. A. Johnson, S. A. Boppart. Intraoperative evaluation of breast tumor margins with optical coherence tomography. Cancer Res., 69, 8790-8796(2009).

    [4] D. S. Gareau, Y. G. Patel, Y. Li, I. Aranda, A. C. Halpern, K. S. Nehal, M. Rajadhyaksha. Confocal mosaicing microscopy in skin excisions: a demonstration of rapid surgical pathology. J. Microsc., 233, 149-159(2009).

    [5] M. Ragazzi, S. Piana, C. Longo, F. Castagnetti, M. Foroni, G. Ferrari, G. Gardini, G. Pellacani. Fluorescence confocal microscopy for pathologists. Mod. Pathol., 27, 460-471(2014).

    [6] T. Pham, B. Banerjee, B. Cromey, S. Mehravar, B. Skovan, H. Chen, K. Kieu. Feasibility of multimodal multiphoton microscopy to facilitate surgical margin assessment in pancreatic cancer. Appl. Opt., 59, G1-G7(2020).

    [7] B. Wang, Q. Zhan, Y. Zhao, R. Wu, J. Liu, S. He. Visible-to-visible four-photon ultrahigh resolution microscopic imaging with 730-nm diode laser excited nanocrystals. Opt. Express, 24, A302-A311(2016).

    [8] F. Fereidouni, Z. T. Harmany, M. Tian, A. Todd, J. A. Kintner, J. D. McPherson, A. D. Borowsky, J. Bishop, M. Lechpammer, S. G. Demos, R. Levenson. Microscopy with ultraviolet surface excitation for rapid slide-free histology. Nat. Biomed. Eng., 1, 957-966(2017).

    [9] T. T. W. Wong, R. Zhang, P. Hai, C. Zhang, M. A. Pleitez, R. L. Aft, D. V. Novack, L. V. Wang. Fast label-free multilayered histology-like imaging of human breast cancer by photoacoustic microscopy. Sci. Adv., 3, e1602168(2017).

    [10] D.-K. Yao. Optimal ultraviolet wavelength for in vivo photoacoustic imaging of cell nuclei. J. Biomed. Opt., 17, 056004(2012).

    [11] T. Yoshitake, M. G. Giacomelli, L. M. Quintana, H. Vardeh, L. C. Cahill, B. E. Faulkner-Jones, J. L. Connolly, D. Do, J. G. Fujimoto. Rapid histopathological imaging of skin and breast cancer surgical specimens using immersion microscopy with ultraviolet surface excitation. Sci. Rep., 8, 4476(2018).

    [12] C. Chiappa, F. Rovera, A. D. Corben, A. Fachinetti, V. De Berardinis, V. Marchionini, S. Rausei, L. Boni, G. Dionigi, R. Dionigi. Surgical margins in breast conservation. Int. J. Surg., 11, S69-S72(2013).

    [13] T. Sellaro, R. Filkins, C. Hoffman, J. Fine, J. Ho, A. Parwani, L. Pantanowitz, M. Montalto. Relationship between magnification and resolution in digital pathology systems. J. Pathol. Inform., 4, 21(2013).

    [14] M. G. L. Gustafsson. Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy. J. Microsc., 198, 82-87(2000).

    [15] E. Mudry, K. Belkebir, J. Girard, J. Savatier, E. Le Moal, C. Nicoletti, M. Allain, A. Sentenac. Structured illumination microscopy using unknown speckle patterns. Nat. Photonics, 6, 312-315(2012).

    [16] F. Schmid, L. Beer. Biological macromolecules: UV-visible spectrophotometry. Encyclopedia of Life Science, 99, 178-181(2001).

    [17] M. Guizar-Sicairos, S. T. Thurman, J. R. Fienup. Efficient subpixel image registration algorithms. Opt. Lett., 33, 156-158(2008).

    [18] L.-H. Yeh, S. Chowdhury, L. Waller. Computational structured illumination for high-content fluorescence and phase microscopy. Biomed. Opt. Express, 10, 1978-1998(2019).

    [19] Y. Zhang, L. Kang, I. H. M. Wong, W. Dai, X. Li, R. C. K. Chan, M. K. Y. Hsin, T. T. W. Wong. High-throughput, label-free and slide-free histological imaging by computational microscopy and unsupervised learning. Adv. Sci., 2102358(2021).

    [20] A. Maiden, D. Johnson, P. Li. Further improvements to the ptychographical iterative engine. Optica, 4, 736-745(2017).

    [21] M. Weigert, U. Schmidt, T. Boothe, A. Müller, A. Dibrov, A. Jain, B. Wilhelm, D. Schmidt, C. Broaddus, S. Culley, M. Rocha-Martins, F. Segovia-Miranda, C. Norden, R. Henriques, M. Zerial, M. Solimena, J. Rink, P. Tomancak, L. Royer, F. Jug, E. W. Myers. Content-aware image restoration: pushing the limits of fluorescence microscopy. Nat. Methods, 15, 1090-1097(2018).

    [22] X. Li, G. Zhang, H. Qiao, F. Bao, Y. Deng, J. Wu, Y. He, J. Yun, X. Lin, H. Xie, H. Wang, Q. Dai. Unsupervised content-preserving transformation for optical microscopy. Light Sci. Appl., 10, 44(2021).

    [23] Y. Zhang, K. de Haan, Y. Rivenson, J. Li, A. Delis, A. Ozcan. Digital synthesis of histological stains using micro-structured and multiplexed virtual staining of label-free tissue. Light Sci. Appl., 9, 78(2020).

    [24] D. S. Gareau. Feasibility of digitally stained multimodal confocal mosaics to simulate histopathology. J. Biomed. Opt., 14, 034050(2009).

    [25] M. G. Giacomelli, L. Husvogt, H. Vardeh, B. E. Faulkner-Jones, J. Hornegger, J. L. Connolly, J. G. Fujimoto. Virtual hematoxylin and eosin transillumination microscopy using epi-fluorescence imaging. PLoS ONE, 11, e0159337(2016).

    [26] G. Barbastathis, A. Ozcan, G. Situ. On the use of deep learning for computational imaging. Optica, 6, 182-192(2021).

    [27] J. Y. Zhu, T. Park, P. Isola, A. A. Efros. Unpaired image-to-image translation using cycle-consistent adversarial networks. IEEE International Conference on Computer Vision (ICCV), 2242-2251(2017).

    [28] Z. Chen, W. Yu, I. H. M. Wong, T. T. W. Wong. Deep-learning-assisted microscopy with ultraviolet surface excitation for rapid slide-free histological imaging. Biomed. Opt. Express, 12, 5920-5938(2021).

    Ivy H. M. Wong, Yan Zhang, Zhenghui Chen, Lei Kang, Terence T. W. Wong. Slide-free histological imaging by microscopy with ultraviolet surface excitation using speckle illumination[J]. Photonics Research, 2022, 10(1): 120
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