• Journal of Innovative Optical Health Sciences
  • Vol. 6, Issue 4, 1350030 (2013)
LINGLING XU1、2, ZHONG-CHAO WEI3, SHAOQUN ZENG1、2, and ZHEN-LI HUANG1、2、*
Author Affiliations
  • 1Britton Chance Center for Biomedical Photonics Wuhan National Laboratory for Optoelectronics-Huazhong University of Science and Technology Wuhan 430074, P. R. China
  • 2Key Laboratory of Biomedical Photonics of Ministry of Education Department of Biomedical Engineering Huazhong University of Science and Technology Wuhan 430074, P. R. China
  • 3Laboratory of Nanophotonic Functional Materials and Devices South China Normal University Guangzhou, 510006, P. R. China
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    DOI: 10.1142/s1793545813500302 Cite this Article
    LINGLING XU, ZHONG-CHAO WEI, SHAOQUN ZENG, ZHEN-LI HUANG. QUANTIFYING THE SHORT LIFETIME WITH TCSPC-FLIM: FIRST MOMENT VERSUS FITTING METHODS[J]. Journal of Innovative Optical Health Sciences, 2013, 6(4): 1350030 Copy Citation Text show less
    References

    [1] P. P. Hsu, D. M. Sabatini, "Cancer cell metabolism: Warburg and beyond," Cell 134, 703 (2008).

    [2] A. Ostman, "The tumor microenvironment controls drug sensitivity," Nat. Med. 18, 1332-1334 (2012).

    [3] C. Stringari, R. A. Edwards, K. T. Pate, M. L. Waterman, P. J. Donovan, E. Gratton, "Metabolic trajectory of cellular differentiation in small intestine by phasor fluorescence lifetime microscopy of NADH," Sci. Rep. 2, srep00568 (2012).

    [4] R. Yasuda, C. D. Harvey, H. N. Zhong, A. Sobczyk, L. van Aelst, K. Svoboda, "Supersensitive Ras activation in dendrites and spines revealed by twophoton fluorescence lifetime imaging," Nat. Neurosci. 9, 283-291 (2006).

    [5] T. Nakabayashi, S. Oshita, R. Sumikawa, F. Sun, M. Kinjo, N. Ohta, "pH dependence of the fluorescence lifetime of enhanced yellow fluorescent protein in solution and cells," J. Photochem. Photobiol. A-Chemistry 235, 65-71 (2012).

    [6] F. A. Gallagher, M. I. Kettunen, S. E. Day, D. E. Hu, J. H. Ardenkjaer-Larsen, R. in't Zandt, P. R. Jensen, M. Karlsson, K. Golman, M. H. Lerche, K. M. Brindle, "Magnetic resonance imaging of pH in vivo using hyperpolarized (13)C-labelled bicarbonate," Nature 453, 940-943 (2008).

    [7] D. Zhao, S. Ran, A. Constantinescu, E. W. Hahn, R. P. Mason, "Tumor oxygen dynamics: Correlation of in vivo MRI with histological findings," Neoplasia 5, 308-318 (2003).

    [8] M. N. Xia, V. Kodibagkar, H. L. Liu, R. P. Mason, "Tumour oxygen dynamics measured simultaneously by near-infrared spectroscopy and F-19 magnetic resonance imaging in rats," Phys. Med. Biol. 51, 45-60 (2006).

    [9] G.-J. Kremers, D. W. Piston, M. W. Davidson, "Fundamental principles of F€orster resonance energy transfer (FRET) microscopy with fluorescent proteins," (2000-2013) Available at http://www. microscopyu.com/articles/fluorescence/fret/fretintro. html.

    [10] M. R. Hight, D. D. Nolting, E. T. McKinley, A. D. Lander, S. K. Wyatt, M. Gonyea, P. Zhao, H. C. Manning, "Multispectral fluorescence imaging to assess pH in biological specimens," J. Biomed. Opt. 16, 016007 (2011).

    [11] M. Y. Berezin, S. Achilefu, "Fluorescence lifetime measurements and biological imaging," Chem. Rev. 110, 2641-2684 (2010).

    [12] C. W. Chang, M. A. Mycek, "Precise fluorophore lifetime mapping in live-cell, multi-photon excitation microscopy," Opt. Express 18, 8688-8696 (2010).

    [13] Y. S. Sun, R. N. Day, A. Periasamy, "Investigating protein-protein interactions in living cells using fluorescence lifetime imaging microscopy," Nat. Protoc. 6, 1324-1340 (2011).

    [14] W. Becker, The bh TCSPC Handbook, 4th Edition, Becker & Hickl GmbH, Germany (2010).

    [15] A. Esposito, H. C. Gerritsen, F. S. Wouters, "Fluorescence lifetime heterogeneity resolution in the frequency domain by lifetime moments analysis," Biophys. J. 89, 4286 (2005).

    [16] W. Becker, Advanced Time-Correlated Single Photon Counting Techniques, 1st Edition, Springer, Berlin (2005).

    [17] D. Trinel, A. Leray, C. Spriet, Y. Usson, L. Heliot, "Upgrading time domain FLIM using an adaptive Monte Carlo data inflation algorithm," Cytometry A 79A, 528-537 (2011).

    [18] V. Sharma, N. Patel, J. Shen, L. Tang, G. Alexandrakis, H. Liu, "A dual-modality optical biopsy approach for in vivo detection of prostate cancer in rat model," J. Innov. Opt. Health Sci. 4, 269-277 (2011).

    [19] W. Becker, A. Bergmann, "Timing stability of TCSPC experiments," in Advanced Photon Counting Techniques, W. Becker, Ed., Proc. SPIE 6372, 637209 (2006).

    [20] W. Becker, SPCImage 3.2 Data Analysis Software for Fluorescence Lifetime Imaging Microscopy, Becker & Hickl GmbH, Berlin (2010).

    [21] Y. Won, S. Moon, W. Yang, D. Kim, W. T. Han, D. Y. Kim, "High-speed confocal fluorescence lifetime imaging microscopy (FLIM) with the analog mean delay (AMD) method," Opt. Express 19, 3396-3405 (2011).

    [22] C. Spriet, D. Trinel, F. Riquet, B. Vandenbunder, Y. Usson, L. Heliot, "Enhanced FRET contrast in lifetime imaging," Cytometry A 73A, 745-753 (2008).

    [23] W. Becker, A. Bergmann, C. Biskup, "Multispectral fluorescence lifetime imaging by TCSPC," Microsc. Res. Tech. 70, 403-409 (2007).

    [24] T. A. Smith, L. M. Hirvonen, C. N. Lincoln, X. Hao, "Deep-UV confocal fluorescence imaging and superresolution optical microscopy of biological samples," J. Innov. Opt. Health Sci. 5, 1250025 (2012).

    [25] L. Xu, L. Wang, Z. Zhang, Z.-L. Huang, "A feasible add-on upgrade on a commercial two-photon FLIM microscope for optimal FLIM-FRET imaging of CFP-YFP Pairs," J. Fluorescence 23, 543-549 (2013).

    [26] M. Szabelski, R. Luchowski, Z. Gryczynski, P. Kapusta, U. Ortmann, I. Gryczynski, "Evaluation of instrument response functions for lifetime imaging detectors using quenched Rose Bengal solutions," Chem. Phys. Lett. 471, 153-159 (2009).

    [27] C. B. Talbot, R. Patalay, I. Munro, S. Warren, F. Ratto, P. Matteini, R. Pini, H. G. Breunig, K. Konig, A. C. Chu, G. W. Stamp, M. A. A. Neil, P. M. W. French, C. Dunsby, "Application of ultrafast gold luminescence to measuring the instrument response function for multispectral multiphoton fluorescence lifetime imaging," Opt. Express 19, 13848-13861 (2011).

    [28] F. Long, S. Q. Zeng, Z. L. Huang, "Localizationbased super-resolution microscopy with an sCMOS camera Part II: Experimental methodology for comparing sCMOS with EMCCD cameras," Opt. Express 20, 17741-17759 (2012).

    [29] J. R. Taylor, An Introduction to Error Analysis: The Study of Uncertainties in Physical Measurements, University Science Books, Sausalito, California (1997).

    LINGLING XU, ZHONG-CHAO WEI, SHAOQUN ZENG, ZHEN-LI HUANG. QUANTIFYING THE SHORT LIFETIME WITH TCSPC-FLIM: FIRST MOMENT VERSUS FITTING METHODS[J]. Journal of Innovative Optical Health Sciences, 2013, 6(4): 1350030
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