[1] Prausnitz M R, Mitragotri S, Langer R. Current status and future potential of transdermal drug delivery[J]. Nature Reviews Drug Discovery, 3, 115-124(2004).

[2] Zaffaroni A. Overview and evolution of therapeutic systems[J]. Annals of the New York Academy of Sciences, 618, 405-421(1991).

[3] Cai B, Söderkvist K, Engqvist H et al. A new drug release method in early development of transdermal drug delivery systems[J]. Pain Research and Treatment, 2012, 953140(2012).

[4] Prausnitz M R, Langer R. Transdermal drug delivery[J]. Nature Biotechnology, 26, 1261-1268(2008).

[5] Bouwstra J A, Honeywell-Nguyen P L, Gooris G S et al. Structure of the skin barrier and its modulation by vesicular formulations[J]. Progress in Lipid Research, 42, 1-36(2003).

[6] Lavon I, Kost J. Ultrasound and transdermal drug delivery[J]. Drug Discovery Today, 9, 670-676(2004).

[7] Ogura M, Paliwal S, Mitragotri S. Low-frequency sonophoresis: current status and future prospects[J]. Advanced Drug Delivery Reviews, 60, 1218-1223(2008).

[8] Lee S, McAuliffe D J, Flotte T J et al. Photomechanical transcutaneous delivery of macromolecules[J]. Journal of Investigative Dermatology, 111, 925-929(1998).

[9] Karande P, Mitragotri S. Dependence of skin permeability on contact area[J]. Pharmaceutical Research, 20, 257-263(2003).

[10] Kost J, Mitragotri S, Gabbay R A et al. Transdermal monitoring of glucose and other analytes using ultrasound[J]. Nature Medicine, 6, 347-350(2000).

[11] Mitragotri S, Coleman M, Kost J et al. Analysis of ultrasonically extracted interstitial fluid as a predictor of blood glucose levels[J]. Journal of Applied Physiology, 89, 961-966(2000).

[12] Mitragotri S, Coleman M, Kost J et al. Transdermal extraction of analytes using low-frequency ultrasound[J]. Pharmaceutical Research, 17, 466-470(2000).

[13] Curdy C, Kalia Y N, Guy R H. Non-invasive assessment of the effects of iontophoresis on human skin in-vivo[J]. The Journal of Pharmacy and Pharmacology, 53, 769-777(2001).

[14] Li G L, van der Geest R, Chanet L et al. In vitro iontophoresis of R-apomorphine across human stratum corneum: structure-transport relationship of penetration enhancement[J]. Journal of Controlled Release, 84, 49-57(2002).

[15] Prausnitz M R. A practical assessment of transdermal drug delivery by skin electroporation[J]. Advanced Drug Delivery Reviews, 35, 61-76(1999).

[16] Lombry C, Dujardin N, Préat V. Transdermal delivery of macromolecules using skin electroporation[J]. Pharmaceutical Research, 17, 32-37(2000).

[17] Mori K J, Hasegawa T, Sato S et al. Effect of electric field on the enhanced skin permeation of drugs by electroporation[J]. Journal of Controlled Release, 90, 171-179(2003).

[18] Vanbever R, Préat V. In vivo efficacy and safety of skin electroporation[J]. Advanced Drug Delivery Reviews, 35, 77-88(1999).

[19] Lee S, Kollias N, McAuliffe D J et al. Topical drug delivery in humans with a single photomechanical wave[J]. Pharmaceutical Research, 16, 1717-1721(1999).

[20] Lee S, McAuliffe D J, Kollias N et al. Permeabilization and recovery of the stratum corneum in vivo: the synergy of photomechanical waves and sodium lauryl sulfate[J]. Lasers in Surgery and Medicine, 29, 145-150(2001).

[21] McAllister D V, Allen M G, Prausnitz M R. Microfabricated microneedles for gene and drug delivery[J]. Annual Review of Biomedical Engineering, 2, 289-313(2000).

[22] Henry S, McAllister D V, Allen M G et al. Microfabricated microneedles: a novel approach to transdermal drug delivery[J]. Journal of Pharmaceutical Sciences, 87, 922-925(1998).

[23] Ahad A, Aqil M, Kohli K et al. Transdermal drug delivery: the inherent challenges and technological advancements[J]. Asian Journal of Pharmaceutical Sciences, 5, 276-288(2010).

[24] Wu J R, Chappelow J, Yang J et al. Defects generated in human stratum corneum specimens by ultrasound[J]. Ultrasound in Medicine & Biology, 24, 705-710(1998).

[25] Mitragotri S, Edwards D A, Blankschtein D et al. A mechanistic study of ultrasonically-enhanced transdermal drug delivery[J]. Journal of Pharmaceutical Sciences, 84, 697-706(1995).

[26] Polat B E, Hart D, Langer R et al. Ultrasound-mediated transdermal drug delivery: mechanisms, scope, and emerging trends[J]. Journal of Controlled Release, 152, 330-348(2011).

[27] Ghosn M G, Sudheendran N, Wendt M et al. Monitoring of glucose permeability in monkey skin in vivo using optical coherence tomography[J]. Journal of Biophotonics, 3, 25-33(2010).

[28] Huang D, Swanson E A, Lin C P et al. Optical coherence tomography[J]. Science, 254, 1178-1181(1991).

[29] Yu T T, Zhu D. Review of tissue optical clearing methods for imaging whole organs[J]. Chinese Journal of Lasers, 47, 0207007(2020).

[30] Xu X Q, Wu L. Dependence of optical clearing effect on tissue structure[J]. Chinese Journal of Lasers, 33, 998-1002(2006).

[31] Zhong H Q, Guo Z Y, Wei H J et al. Effects of ultrasound and glycerol on skin optical clearing[J]. Chinese Journal of Lasers, 36, 2503-2509(2009).

[32] Tuchin V V. Optical clearing of tissues and blood using the immersion method[J]. Journal of Physics D: Applied Physics, 38, 2497-2518(2005).

[33] Jiang J Y, Boese M, Turner P H et al. Penetration kinetics of dimethyl sulphoxide and glycerol in dynamic optical clearing of porcine skin tissue in vitro studied by Fourier transform infrared spectroscopic imaging[J]. Journal of Biomedical Optics, 13, 021105(2008).

[34] Kuranov R V, Sapozhnikova V V, Prough D S et al. In vivo study of glucose-induced changes in skin properties assessed with optical coherence tomography[J]. Physics in Medicine and Biology, 51, 3885-3900(2006).

[35] Larina I V, Carbajal E F, Tuchin V V et al. Enhanced OCT imaging of embryonic tissue with optical clearing[J]. Laser Physics Letters, 5, 476-479(2008).

[36] Wei H J, Wu G Y, Guo Z Y et al. Assessment of the effects of ultrasound-mediated glucose on permeability of normal, benign, and cancerous human lung tissues with the Fourier-domain optical coherence tomography[J]. Journal of Biomedical Optics, 17, 116006(2012).

[37] Xu X Q, Zhu Q H. Feasibility of sonophoretic delivery for effective skin optical clearing[J]. IEEE Transactions on Biomedical Engineering, 55, 1432-1437(2008).

[38] Xu X Q, Zhu Q H. Sonophoretic delivery for contrast and depth improvement in skin optical coherence tomography[J]. IEEE Journal of Selected Topics in Quantum Electronics, 14, 56-61(2008).

[39] Khan M H, Choi B, Chess S et al. Optical clearing of in vivo human skin: implications for light-based diagnostic imaging and therapeutics[J]. Lasers in Surgery and Medicine, 34, 83-85(2004).

[40] Whiteside P J D, Qian C X, Golda N et al. Ultrasonic modulation of tissue optical properties in ex vivo porcine skin to improve transmitted transdermal laser intensity[J]. Lasers in Surgery and Medicine, 49, 666-674(2017).

[41] Park D, Song G, Jo Y et al. Sonophoresis using ultrasound contrast agents: dependence on concentration[J]. PLoS One, 11, e0157707(2016).

[42] Zhong H, Guo Z, Wei H et al. Synergistic effect of ultrasound and thiazone-PEG 400 on human skin optical clearing in vivo[J]. Photochemistry and Photobiology, 86, 732-737(2010).

[43] Genina E A, Svenskaya Y I, Yanina I Y et al. In vivo optical monitoring of transcutaneous delivery of calcium carbonate microcontainers[J]. Biomedical Optics Express, 7, 2082-2087(2016).

[44] Xu X Q, Sun C J. Ultrasound enhanced skin optical clearing: microstructural changes[J]. Journal of Innovative Optical Health Sciences, 3, 189-194(2010).

[45] Guo X, Guo Z Y, Wei H J et al. In vivo comparison of the optical clearing efficacy of optical clearing agents in human skin by quantifying permeability using optical coherence tomography[J]. Photochemistry and Photobiology, 87, 734-740(2011).

[46] Zhang Y Q, Wei H J, Yang H Q et al. Noninvasive blood glucose monitoring during oral intake of different sugars with optical coherence tomography in human subjects[J]. Journal of Biophotonics, 6, 699-707(2013).

[47] He R Y, Wei H J, Gu H M et al. Effects of optical clearing agents on noninvasive blood glucose monitoring with optical coherence tomography: a pilot study[J]. Journal of Biomedical Optics, 17, 101513(2012).

[48] Zhong H Q, Guo Z Y, Wei H J et al. Enhancement of permeability of glycerol with ultrasoundin human normal and cancer breast tissues in vitro using optical coherence tomography[J]. Laser Physics Letters, 7, 388-395(2010).

[49] Zhao Q L, Si J L, Guo Z Y et al. Quantifying glucose permeability and enhanced light penetration in ex vivo human normal and cancerous esophagus tissues with optical coherence tomography[J]. Laser Physics Letters, 8, 71-77(2011).

[50] Stumpp O, Chen B, Welch A J. Using sandpaper for noninvasive transepidermal optical skin clearing agent delivery[J]. Journal of Biomedical Optics, 11, 041118(2006).

[51] Zhong H Q, Guo Z Y, Wei H J et al. In vitro study of ultrasound and different-concentration glycerol-induced changes in human skin optical attenuation assessed with optical coherence tomography[J]. Journal of Biomedical Optics, 15, 036012(2010).

[52] Zhang Y Q, Wei H J, Yang H Q et al. In vitro study of the effects of ultrasound-mediated glycerol on optical attenuation of human normal and cancerous esophageal tissues with optical coherence tomography[J]. Laser Physics, 23, 065604(2013).

[53] Zhu Z, Wu G, Wei H et al. Investigation of the permeability and optical clearing ability of different analytes in human normal and cancerous breast tissues by spectral domain OCT[J]. Journal of Biophotonics, 5, 536-543(2012).

[54] Park D, Yoon J, Park J et al. Transdermal drug delivery aided by an ultrasound contrast agent: an in vitro experimental study[J]. The Open Biomedical Engineering Journal, 4, 56-62(2010).

[55] Escobar-Chávez J J, Bonilla-Martínez D, Villegas-González M A et al. The use of sonophoresis in the administration of drugs throughout the skin[J]. Journal of Pharmacy & Pharmaceutical Sciences, 12, 88-115(2009).

[56] Yoon J, Park D, Son T et al. A physical method to enhance transdermal delivery of a tissue optical clearing agent: combination of microneedling and sonophoresis[J]. Lasers in Surgery and Medicine, 42, 412-417(2010).

[57] Buranachai C, Thavarungkul P, Kanatharana P et al. Application of wavelet analysis in optical coherence tomography for obscured pattern recognition[J]. Laser Physics Letters, 6, 892-895(2009).