• Laser & Optoelectronics Progress
  • Vol. 59, Issue 10, 1017001 (2022)
Yue Zou1、2, Huajiang Wei1、2、*, Hongqin Yang3, Shusen Xie3, and Guoyong Wu4
Author Affiliations
  • 1Key Laboratory of Laser Life Science, Ministry of Education, College of Biophotonics, South China Normal University, Guangzhou 510631, Guangdong , China
  • 2Guangdong Provincial Key Laboratory of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou 510631, Guangdong , China
  • 3Key Laboratory of Optoelectronic Science and Technology for Medicine, Ministry of Education, Fujian Normal University, Fuzhou 350007, Fujian , China
  • 4Department of Surgery, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, Guangdong , China
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    DOI: 10.3788/LOP202259.1017001 Cite this Article Set citation alerts
    Yue Zou, Huajiang Wei, Hongqin Yang, Shusen Xie, Guoyong Wu. Effect of Pulsed Ultrasonic Intensities on Glycerol Permeability and Light Penetration Depth in Human Skin in vivo[J]. Laser & Optoelectronics Progress, 2022, 59(10): 1017001 Copy Citation Text show less
    Changes of OCT signal in human skin. (a) OCT signal measurement area indicating OCTSS recorded on human skin; (b) corresponding OCT intensity profile as a function of depth after ultrasonic action with intensity of 0.8 W/cm2 for 5 min and 45 min on human skin applying 30% glycerol solution
    Fig. 1. Changes of OCT signal in human skin. (a) OCT signal measurement area indicating OCTSS recorded on human skin; (b) corresponding OCT intensity profile as a function of depth after ultrasonic action with intensity of 0.8 W/cm2 for 5 min and 45 min on human skin applying 30% glycerol solution
    Curves of OCTSS with time. (a) 15% glycerol; (b) 30% glycerol; (c) 15% glycerol+0.2 W/cm2 ultrasound; (d) 30% glycerol+0.2 W/cm2 ultrasound; (e) 15% glycerol+0.4 W/cm2 ultrasound; (f) 30% glycerol+0.4 W/cm2 ultrasound; (g) 15% glycerol+0.6 W/cm2 ultrasound; (h) 30% glycerol+0.6 W/cm2 ultrasound; (i) 15% glycerol+0.8 W/cm2 ultrasound; (j) 30% glycerol+0.8 W/cm2 ultrasound
    Fig. 2. Curves of OCTSS with time. (a) 15% glycerol; (b) 30% glycerol; (c) 15% glycerol+0.2 W/cm2 ultrasound; (d) 30% glycerol+0.2 W/cm2 ultrasound; (e) 15% glycerol+0.4 W/cm2 ultrasound; (f) 30% glycerol+0.4 W/cm2 ultrasound; (g) 15% glycerol+0.6 W/cm2 ultrasound; (h) 30% glycerol+0.6 W/cm2 ultrasound; (i) 15% glycerol+0.8 W/cm2 ultrasound; (j) 30% glycerol+0.8 W/cm2 ultrasound
    Comparison of mean permeability coefficients of 15% glycerol solution/SP, 30% glycerol solution/SP diffusion in human skin in vivo
    Fig. 3. Comparison of mean permeability coefficients of 15% glycerol solution/SP, 30% glycerol solution/SP diffusion in human skin in vivo
    1/e light penetration depths change as a function of time. (a) 15% glycerol/SP; (b) 30% glycerol/SP
    Fig. 4. 1/e light penetration depths change as a function of time. (a) 15% glycerol/SP; (b) 30% glycerol/SP
    Yue Zou, Huajiang Wei, Hongqin Yang, Shusen Xie, Guoyong Wu. Effect of Pulsed Ultrasonic Intensities on Glycerol Permeability and Light Penetration Depth in Human Skin in vivo[J]. Laser & Optoelectronics Progress, 2022, 59(10): 1017001
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