• Laser & Optoelectronics Progress
  • Vol. 58, Issue 4, 0400001 (2021)
Jianwei Chen1、2、3, Hui Gong1、2、3, and Jing Yuan1、2、3、*
Author Affiliations
  • 1Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China
  • 2MoE Key Laboratory for Biomedical Photonics, School of Engineering Sciences, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China
  • 3HUST-Suzhou Institute for Brainsmatics, Suzhou, Jiangsu 215125, China
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    DOI: 10.3788/LOP202158.0400001 Cite this Article Set citation alerts
    Jianwei Chen, Hui Gong, Jing Yuan. Multispectral Imaging Technology and Its Applications in Biomedicine[J]. Laser & Optoelectronics Progress, 2021, 58(4): 0400001 Copy Citation Text show less
    MSI systems based on different spectral separation elements[19]. (a) Rotating filter; (b) liquid crystal tunable filter; (c) planar compound eye imaging system; (d) multi-layer curved compound eye MSI system
    Fig. 1. MSI systems based on different spectral separation elements[19]. (a) Rotating filter; (b) liquid crystal tunable filter; (c) planar compound eye imaging system; (d) multi-layer curved compound eye MSI system
    Smartphone-based portable MSI system
    Fig. 2. Smartphone-based portable MSI system
    Multispectral microscopic imaging systems. (a) Multi-wavelength fluorescent microscopy; (b) fiber-based multispectral endomicroscopy; (c) multispectral optoacoustic tomography
    Fig. 3. Multispectral microscopic imaging systems. (a) Multi-wavelength fluorescent microscopy; (b) fiber-based multispectral endomicroscopy; (c) multispectral optoacoustic tomography
    Multilayer composite metasurfaces used for multispectral achromatic imaging[37]. (a) Diagram of multilayer composite structure; (b) spectrum taken under white light illumination and distribution of focal spot of red light (650 nm); (c) foci of three characteristic peaks
    Fig. 4. Multilayer composite metasurfaces used for multispectral achromatic imaging[37]. (a) Diagram of multilayer composite structure; (b) spectrum taken under white light illumination and distribution of focal spot of red light (650 nm); (c) foci of three characteristic peaks
    MSI technology used for skin tissue detection. (a) Multispectral imaging for skin slice via NIR MSI to distinguish healthy tissues from diseased tissues[51]; (b) MSOT for in vivo detection of skin melanin and blood oxygenation level[52]
    Fig. 5. MSI technology used for skin tissue detection. (a) Multispectral imaging for skin slice via NIR MSI to distinguish healthy tissues from diseased tissues[51]; (b) MSOT for in vivo detection of skin melanin and blood oxygenation level[52]
    Assessment of breast tumor margins via MSOT[59]. (a) Ultrasound image of the excised specimen. Dashed area is tumor tissue; (b) multispectral optoacoustic image shows lipids and deoxyhemoglobin; (c) enlarged view shows that deoxyhemoglobin signal can be used to identify tumor margin
    Fig. 6. Assessment of breast tumor margins via MSOT[59]. (a) Ultrasound image of the excised specimen. Dashed area is tumor tissue; (b) multispectral optoacoustic image shows lipids and deoxyhemoglobin; (c) enlarged view shows that deoxyhemoglobin signal can be used to identify tumor margin
    Multispectral biometric feature recognition. (a) Extract and analyze multispectral characteristics of conjunctival vessels and iris textures[66]; (b) quaternion model for multispectral palmprint information recognition[74]; (c) hierarchical fusion of multi-spectral images and feature of face for face recognition[83]
    Fig. 7. Multispectral biometric feature recognition. (a) Extract and analyze multispectral characteristics of conjunctival vessels and iris textures[66]; (b) quaternion model for multispectral palmprint information recognition[74]; (c) hierarchical fusion of multi-spectral images and feature of face for face recognition[83]
    Jianwei Chen, Hui Gong, Jing Yuan. Multispectral Imaging Technology and Its Applications in Biomedicine[J]. Laser & Optoelectronics Progress, 2021, 58(4): 0400001
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