A new cross-calibration method is proposed. In this method, hyperspectral imager Hyperion is used as reference sensor, Terra and MODIS are used as sensor to be calibrated, and Dunhuang site is selected as target, with matching elements including field, time, geometry and spectrum considered in the process of cross-calibration. At-sensor radiances of fourteen bands of MODIS are predicted, and the predicted values are then compared with the measured values of corresponding bands. The results show that the differences of thirteen bands are no more than 7.7%, and the difference of the ninth bands is 11.9%. The total uncertainties of cross-calibration are superior to 7.7%. The principle feasibility of the new method is validated.