Local-Connection-Network-Based Reconstruction Method for Cerenkov Luminescence Tomography

Weitong Li; Haolin Wang; Kang Li; Guohua Geng; Mingquan Zhou; Xin Cao

doi:10.3788/LOP202259.0617031

Journals >Laser & Optoelectronics Progress >Volume 59 >Issue 6 >Page 0617031 > Article

Laser & Optoelectronics Progress
Vol. 59, Issue 6, 0617031 (2022)

Local-Connection-Network-Based Reconstruction Method for Cerenkov Luminescence Tomography

Weitong Li¹, Haolin Wang¹, Kang Li¹, Guohua Geng¹, Mingquan Zhou², and Xin Cao^1、*

Author Affiliations

¹School of Information Science & Technology, Northwest University, Xi'an , Shaanxi 710127, China

²College of Information Science and Technology, Beijing Normal University, Beijing 100875, China

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DOI: 10.3788/LOP202259.0617031 Cite this Article Set citation alerts

Weitong Li, Haolin Wang, Kang Li, Guohua Geng, Mingquan Zhou, Xin Cao. Local-Connection-Network-Based Reconstruction Method for Cerenkov Luminescence Tomography[J]. Laser & Optoelectronics Progress, 2022, 59(6): 0617031 Copy Citation Text

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Fig. 1. FES-LCN structure

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Research object of inhomogeneous cylinder simulation experiment. (a) Inhomogeneous cylinder model; (b) example of grid model of inhomogeneous cylinder; (c) example of forward simulation result of inhomogeneous cylinder

Fig. 2. Research object of inhomogeneous cylinder simulation experiment. (a) Inhomogeneous cylinder model; (b) example of grid model of inhomogeneous cylinder; (c) example of forward simulation result of inhomogeneous cylinder

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Fig. 3. Reconstructed results in inhomogeneous cylinder simulation experiment with single light source. (a) Stereogram reconstructed by IVTCG; (b) stereogram reconstructed by MFCNN; (c) stereogram reconstructed by FES-LCN; (d) two-dimensional section of reconstructed result for IVTCG; (e) two-dimensional section of reconstructed result for MFCNN; (f) two-dimensional section of reconstructed result for FES-LCN

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Fig. 4. Reconstruction results in inhomogeneous cylinder simulation experiment with dual light source. (a) Stereogram reconstructed by IVTCG; (b) stereogram reconstructed by MFCNN; (c) stereogram reconstructed by FES-LCN; (d) two-dimensional section of reconstructed result for IVTCG; (e) two-dimensional section of reconstructed result for MFCNN; (f) two-dimensional section of reconstructed result for FES-LCN

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Fig. 5. Research object of digital mouse simulation experiment. (a) Digital mouse model; (b) example of grid model of digital mouse; (c) example of forward simulation result of digital mouse

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Fig. 6. Reconstruction results in digital mouse simulation experiment with single light source. (a) Stereogram reconstructed by IVTCG; (b) stereogram reconstructed by MFCNN; (c) stereogram reconstructed by FES-LCN; (d) two-dimensional section of reconstructed result for IVTCG; (e) two-dimensional section of reconstructed result for MFCNN; (f) two-dimensional section of reconstructed result for FES-LCN

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Fig. 7. Reconstruction results in digital mouse simulation experiment with dual light source. (a) Stereogram reconstructed by IVTCG; (b) stereogram reconstructed by MFCNN; (c) stereogram reconstructed by FES-LCN; (d) two-dimensional section of reconstructed result for IVTCG; (e) two-dimensional section of reconstructed result for MFCNN; (f) two-dimensional section of reconstructed result for FES-LCN

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Material	$μ_{a x}$ /mm^-1	$μ_{s x}$ /mm^-1
Muscle	0.0052	10.8
Heart	0.0083	6.733
Lung	0.0133	19.7
Liver	0.0329	7.0
Bone	0.0060	60.09

Table 1. Optical parameters of inhomogeneous cylinder

Method	Coordinate of the center of reconstructed light source	Coordinate of the point with maximum energy	$E_{C}$	$E_{L}$	$R_{T V}$
IVTCG	（-1.65，3.18，10.87）	（-1.60，2.95，11.01）	0.682	0.603	0.57
MFCNN	（-1.12，2.92，11.08）	（-1.60，2.95，11.01）	0.171	0.603	1.23
FES-LCN	（-1.12，2.92，11.08）	（-0.87，3.45，11.05）	0.171	0.469	0.68

Table 2. Results of three reconstruction methods in inhomogeneous cylinder simulation experiment with single light source

Method

Coordinate of center of reconstructed light source

Coordinate of the point with maximum energy

E_{C}

E_{L}

R_{T V}

IVTCG

（-5.61，2.74，8.12）

（-3.02，2.91，9.60）

（-4.31，3.20，8.62）

（-3.37，2.87，9.09）

1.472

2.429

1.52

MFCNN

（-5，65，2.85，8.08）

（-1.07，2.95，10.79）

（-5.48，2.35，8.26）

（-1.6，2.95，11.01）

0.309

0.735

1.06

FES-LCN

（-5，65，2.85，8.08）

（-1.07，2.95，10.79）

（-5.48，2.35，8.26）

（-0.87，3.45，11.05）

0.309

0.668

1.00

Table 3. Results of three reconstruction methods in inhomogeneous cylinder simulation experiment with dual light source

Method	Coordinate of the center of reconstructed light source	Coordinate of the point with maximum energy	$E_{C}$	$E_{L}$	$R_{T V}$
IVTCG	（18.89，7.98，19.24）	（19.40，8.36，19.15）	1.672	1.081	0.43
MFCNN	（18.58，7.21，19.23）	（18.14，7.18，18.61）	0.346	0.981	1
FES-LCN	（18.58，7.21，19.23）	（17.97，6.35，19.35）	0.345	0.852	1