To effectively improve the wear resistance of TC4 alloy, TC4 + NiCr/Cr3C2 is used as the cladding material. In addition, the TiC-reinforced Ti-based coating is prepared on the TC4 alloy surface using the TRUMPF 4002 coaxial powder-feeding laser. Using various experimental characterization techniques and test equipments, the microstructure and wear resistance of the coating are investigated and analyzed. The results indicate that the cladding layer formation is mainly composed of the reinforcing phase TiC and the continuous matrix phase α-Ti. The TiC in the subsurface layer of the coating is mainly in the form of granular phase; the middle region, in the form of dendrite phase; the bonding zone, in the form of feather phase. The Ni, Cr, Al, and V elements, which are matrix solid solution elements, form reaction precipitates with the Ti element. The improvement in the average microhardness （536 HV0.5） of the coating is attributed to the TiC and strengthening solid solution of the Ni, Cr, Al, and V elements in the matrix, and the microhardness is approximately 50% higher than the microhardness of the TC4 substrate. The wear volume and friction coefficient of the coating are 27% and 25% lower than those of the TC4 substrate, respectively, with the wear mechanism being abrasive wear.