Research Progress and Application of Cardiovascular Optical Coherence Tomography

Yingzhao Wei; Xing Yuan; Gongpu Lan; Yanping Huang; Jia Qin; Lin An; Haishu Tan; Shangjie Ren; Shiyong Zhao; Jiaqi Bie; Haibo Jia; Bo Yu; Jingjiang Xu

doi:10.3788/LOP202158.2400002

Journals >Laser & Optoelectronics Progress >Volume 58 >Issue 24 >Page 2400002 > Article

Laser & Optoelectronics Progress
Vol. 58, Issue 24, 2400002 (2021)

Research Progress and Application of Cardiovascular Optical Coherence Tomography

Yingzhao Wei¹, Xing Yuan¹, Gongpu Lan^2、3、4, Yanping Huang^2、3、4, Jia Qin^2、3、4, Lin An^2、3、4, Haishu Tan^2、3, Shangjie Ren⁵, Shiyong Zhao⁶, Jiaqi Bie⁷, Haibo Jia⁸, Bo Yu⁸, and Jingjiang Xu^{2、3、4、*}

Author Affiliations

¹School of Mechatronic Engineering and Automation, Foshan University, Foshan, Guangdong 528200, China

²School of Physics and Optoelectronic Engineering, Foshan University, Foshan, Guangdong 528200, China

³Guangdong-Hong Kong-Macao Intelligent Micro-Nano Optoelectronic Technology Joint Laboratory, Foshan University, Foshan, Guangdong 528200, China

⁴Innovation and Entrepreneurship Teams Project of Guangdong Pearl River Talents Program, Guangdong Weiren Meditech Co., Ltd., Foshan, Guangdong 528000, China

⁵Tianjin Key Laboratory of Process Measurement and Control, School of Electrical and Information Engineering, Tianjin University, Tianjin 300072, China

⁶Tianjin Horimed Technology Co., Ltd, Tianjin 300000, China

⁷School of Astronautics, Harbin Institute of Technology, Harbin, Heilongjiang 150001, China

⁸Department of Cardiology, The 2nd Affiliated Hospital of Harbin Medical University, Key Laboratory of Medical Ischemia, Chinese Ministry of Education, Harbin, Heilongjiang 150001, China

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DOI: 10.3788/LOP202158.2400002 Cite this Article Set citation alerts

Yingzhao Wei, Xing Yuan, Gongpu Lan, Yanping Huang, Jia Qin, Lin An, Haishu Tan, Shangjie Ren, Shiyong Zhao, Jiaqi Bie, Haibo Jia, Bo Yu, Jingjiang Xu. Research Progress and Application of Cardiovascular Optical Coherence Tomography[J]. Laser & Optoelectronics Progress, 2021, 58(24): 2400002 Copy Citation Text

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Number of PCI cases and its growth rate in China in the past decade (the data was plotted according to the annual report from CCIF2011 to CCIF2019). (a) Number of PCI cases in China in the past decade; (b) growth rate of PCI cases in China in the past decade

Fig. 1. Number of PCI cases and its growth rate in China in the past decade (the data was plotted according to the annual report from CCIF2011 to CCIF2019). (a) Number of PCI cases in China in the past decade; (b) growth rate of PCI cases in China in the past decade

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Fig. 2. Structural diagrams of three generations of OCT systems. (a) Time domain OCT; (b) spectral domain OCT; (c) swept source OCT

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Fig. 3. Number of publications about OCT applied to fields of ophthalmology, cardiology, dermatology, and gastroenterology in 1991—2019 (the data was obtained from annual PubMed publications)

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Fig. 4. Number of publications about OCT endoscopic imaging applied to fields of cardiovascular, esophagus, respiratory tract, and gastrointestinal tract in 1995—2019 (the data was obtained from annual PubMed publications)

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Fig. 5. Schematics of OCT scanning probe design for different endoscopes^[30]. (a) Side-viewing endoscopic OCT scanning probe; (b) forward-viewing endoscopic OCT scanning probe; (c) proximal scanning fiber rotating probe; (d) distal-scanning endoscope with micromotor

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Fig. 6. Schematic of the first single mode fiber based endoscopic catheter^[26]. (a) Optical rotatory connector; (b) distal end of catheter

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Fig. 7. Commercial OCT imaging catheter

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Fig. 8. Representative commercial intravascular OCT products of different types

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Fig. 9. OCT images of normal coronary vessels and representative plaque and coronary microstructures

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Fig. 10. Representative OCT images for stent evaluation. (a) Stent malapposition; (b) in-stent restenosis; (c) stent thrombosis

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Product	M2	M3	C7XR^TM	ILUMIEN^TM	ILUMIEN^TMOPTIS^TM
Release time	2004	2007	2009	2011	2012
Type of OCT	TD-OCT	TD-OCT	SS-OCT	SS-OCT	SS-OCT
Product feature	1^st commercial OCT, occlusion+flush	2^nd generation OCT, occlusion +flush	CE mark & FDA approval, occlusion-free	Combined wireless FFR and OCT	Advanced software tools of PCI optimization, tableside control from DOC
Key specification	Line speed: 3 kHz; frame speed: 15 frame·s^-1; number of lines: 200	Line speed: 4.8 kHz; frame speed: 20 frame·s^-1; number of lines: 240	Line speed: 50 kHz; frame speed: 100 frame·s^-1; number of lines: 500	Frame speed: 100 frame·s^-1; number of lines: 500; 54 mm pullback length	Line speed: 90 kHz; frame speed: 180 frame·s^-1; number of lines: 500; 54 mm/75 mm pullback length
Vendor	LightLab Imaging	LightLab Imaging	LightLab Imaging	St. Jude Medical	St. Jude Medical

Table 1. Important parameter information of different commercial intravascular OCT products of different types

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