The finite-difference time-domain method is used to simulate uniform moth-eye structure (UMS) and bi-hybrid moth-eye structure (BHMS). The influences of height and bottom diameter on the reflectance are analyzed, and the anti-reflection properties of UMS and BHMS are compared. The superior anti-reflection property of BHMS is analyzed based on the reflectance curves and the electric field intensity distribution. The results show that the reflectance of UMS decreases with the increase of height, and decreases and then increases with the increase of bottom diameter in the wavelength range of 300-1200 nm. The average reflectance of BHMS consisting of UMS with different heights is greater than the minimum average reflectance of the corresponding UMS when the bottom diameter is 250 nm. The anti-reflection property of BHMS consisting of UMS with different bottom diameters can be further improved.