Determination of Thallium in Blood of Occupational Exposed Population by Inductively Coupled Plasma Mass Spectrometry With High Matrix Introduction

Fei ZHANG; Xia HUA; Jia-ying YUAN; Fan YOU; Ren-cai YE; Li DING; Jian-mei ZHAO

doi:10.3964/j.issn.1000-0593(2022)09-2870-05

Journals >Spectroscopy and Spectral Analysis >Volume 42 >Issue 9 >Page 2870 > Article

Spectroscopy and Spectral Analysis
Vol. 42, Issue 9, 2870 (2022)

Determination of Thallium in Blood of Occupational Exposed Population by Inductively Coupled Plasma Mass Spectrometry With High Matrix Introduction

Fei ZHANG^{1、1; 5;}, Xia HUA^{2、2; *;}, Jia-ying YUAN^3、3;, Fan YOU^1、1;, Ren-cai YE^4、4;, Li DING^4、4;, and Jian-mei ZHAO^4、4;

Author Affiliations

¹1. Sichuan Center for Disease Control and Prevention, Chengdu 610041, China

²2. Sichuan Center for Food and Drug Evaluation, Inspection & Monitoring, Chengdu 610017, China;

³3. Chengdu University of Traditional Chinese Medicine, Chengdu 610032, China

⁴4. Liangshan Zhou Center for Disease Control and Prevention, Liangshan 615000, China

show less

DOI: 10.3964/j.issn.1000-0593(2022)09-2870-05 Cite this Article

Fei ZHANG, Xia HUA, Jia-ying YUAN, Fan YOU, Ren-cai YE, Li DING, Jian-mei ZHAO. Determination of Thallium in Blood of Occupational Exposed Population by Inductively Coupled Plasma Mass Spectrometry With High Matrix Introduction[J]. Spectroscopy and Spectral Analysis, 2022, 42(9): 2870 Copy Citation Text

show less

Fig. 1. Mass spectrogram of standard series and internal standard (a); Standard curve equation of thallium (b)

Download full size | View in the Article

Fig. 2. Variation of internal standard element signals

Download full size | View in the Article

参数	设定值
RF power	1 550 W
Cool gas flow	15.0 L·min^-1
Auxiliary gas flow	0.90 L·min^-1
Plasma gas flow	15 L·min^-1
Nebulizer pump speed	0.1 r·min^-1
Carrier gas flow rate	1.05 L·min^-1
Acquisition mode	Mass spectrogram
Tuning mode	No Gas
Plasma mode	HMI

Table 1. Instrumental parameters for HMI-ICP-MS

View in the Article

冻干全血质量控制样品	方法	测定值/(μg·L^-1)	精密度/%	误差/%	参考值范围/(μg·L^-1)
	1	11.7, 10.9, 11.0, 11.4, 11.0, 12.8	6.28	11.9
	2	11.0, 10.5, 11.5, 10.2, 10.7, 9.75	5.77	4.79
L-2	3	10.6, 10.8, 10.2, 9.91, 10.7, 10.6	3.26	3.52	10.1(8.1~12.1)
	4	11.2, 11.2, 11.9, 10.9, 11.6, 10.8	3.71	10.4
	5	10.3, 11.1, 11.3, 11.1, 10.7, 10.2	4.25	6.34
	1	32.7, 31.5, 34.4, 33.8, 30.9, 34.2	4.45	3.39
	2	34.4, 33.9, 31.1, 33.8, 34.7, 32.6	4.02	4.84
L-3	3	33.4, 31.9, 33.8, 31.8, 32.4, 32.5	2.47	2.55	31.8(29.0~34.5)
	4	33.8, 32.9, 34.3, 34.5, 31.3, 32.2	3.80	4.12
	5	33.5, 34.5, 32.1, 33.1, 34.2, 33.2	2.56	4.89

Table 2. Analytical results of thallium in blood under different treatments by HMI-ICP-MS (n=6)

View in the Article

本底 /(μg·L^-1)	加标 /(μg·L^-1)	测得值/(μg·L^-1)	回收率 /%	批内精密度 /%	批间精密度 /%
<0.42	2.50	2.63, 2.70, 2.60, 2.59, 2.55, 2.61, 2.49	103.8	2.52	-
<0.42	2.50	2.71, 2.45, 2.61, 2.44, 2.57, 2.38, 2.64	101.7	-	4.77
<0.42	15.0	15.2, 15.7, 16.3, 15.3, 15.2, 15.6, 16.1	104.2	2.81	-
<0.42	15.0	15.4, 14.0, 14.2, 15.4, 14.9, 15.1, 13.9	92.7	-	4.44
<0.42	75.0	75.6, 74.8, 73.7, 72.9, 75.2, 72.1, 74.3	98.8	1.71	-
<0.42	75.0	75.4, 76.5, 77.3, 72.9, 71.2, 74.6, 73.6	99.3	-	2.84

Table 3. Recovery and precision of the method (n=7)

Download Citation

Save the article for my favorites

Paper Information