• Laser & Optoelectronics Progress
  • Vol. 55, Issue 12, 120001 (2018)
Mengcong Du1、2, Qianqian Liu1、2, Lang Marion1、2, Xiuhong Wang1、2、*, and Pu Wang1、2
Author Affiliations
  • 1 Institute of Laser Engineering, Beijing University of Technology, Beijing 100124, China
  • 2 Beijing Engineering Research Center of Applied Laser Technology, Beijing 100124, China
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    DOI: 10.3788/LOP55.120001 Cite this Article Set citation alerts
    Mengcong Du, Qianqian Liu, Lang Marion, Xiuhong Wang, Pu Wang. Research Progress and Application of Cell Lasers[J]. Laser & Optoelectronics Progress, 2018, 55(12): 120001 Copy Citation Text show less
    Schematic of cell lasers based on Fabry-Perot cavity
    Fig. 1. Schematic of cell lasers based on Fabry-Perot cavity
    Emission and absorption spectra of GFP[17]
    Fig. 2. Emission and absorption spectra of GFP[17]
    Emission spectra at different pump wavelengths[17]
    Fig. 3. Emission spectra at different pump wavelengths[17]
    Installation diagram of single cell lasers[17]
    Fig. 4. Installation diagram of single cell lasers[17]
    Laser output energy as a function of pump energy[17]
    Fig. 5. Laser output energy as a function of pump energy[17]
    Output spectra for pump energies of 0.9 nJ (a) and 5 nJ (b), respectively[17]
    Fig. 6. Output spectra for pump energies of 0.9 nJ (a) and 5 nJ (b), respectively[17]
    Schematic of whispering gallery mode
    Fig. 7. Schematic of whispering gallery mode
    Injected oil droplet cell lasers[57]
    Fig. 8. Injected oil droplet cell lasers[57]
    Output spectrum of injected oil droplet lasers[57]
    Fig. 9. Output spectrum of injected oil droplet lasers[57]
    Confocal image of an adipocyte containing a large lipid droplet (orange)[57]
    Fig. 10. Confocal image of an adipocyte containing a large lipid droplet (orange)[57]
    Physical device diagram of porcine skin cell laser[57]
    Fig. 11. Physical device diagram of porcine skin cell laser[57]
    Output spectrum of adipocyte[57]
    Fig. 12. Output spectrum of adipocyte[57]
    Three types of microsphere resonators and their output spectra[57]. (a) Gain in microspheres; (b) gain outside microspheres; (c) gain on the surface of microspheres
    Fig. 13. Three types of microsphere resonators and their output spectra[57]. (a) Gain in microspheres; (b) gain outside microspheres; (c) gain on the surface of microspheres
    Comparison of fluorescence-based detection and laser-based detection[58]. (a) Fluorescence signal; (b) laser-based signal
    Fig. 14. Comparison of fluorescence-based detection and laser-based detection[58]. (a) Fluorescence signal; (b) laser-based signal
    BaTio3 microsphere during HeLa cell division[59]. (a) Bright-field images of microspheres in cells; (b) measured spectral shifts of mitosis progress
    Fig. 15. BaTio3 microsphere during HeLa cell division[59]. (a) Bright-field images of microspheres in cells; (b) measured spectral shifts of mitosis progress
    Polystyrene microsphere images and corresponding emission spectra of 3T3 cell division process[60]. Mother cells are denoted as A (red) and subsequent daughter generations are labeled with B (blue), C (violet) and D (orange), respectively
    Fig. 16. Polystyrene microsphere images and corresponding emission spectra of 3T3 cell division process[60]. Mother cells are denoted as A (red) and subsequent daughter generations are labeled with B (blue), C (violet) and D (orange), respectively
    Living cell biological analysis device[58]
    Fig. 17. Living cell biological analysis device[58]
    Corresponding diameters of hyperspectral image of microspheres[57]
    Fig. 18. Corresponding diameters of hyperspectral image of microspheres[57]
    Emission spectra of each cell at 0, 7, 19 h and bright-field images of each cell at 0 h[60]
    Fig. 19. Emission spectra of each cell at 0, 7, 19 h and bright-field images of each cell at 0 h[60]
    Schematic of the microfluidic chip setup[61]
    Fig. 20. Schematic of the microfluidic chip setup[61]
    Spectrum barcod after data processing[61]
    Fig. 21. Spectrum barcod after data processing[61]
    Schematic of cell lasers for imaging source[58]
    Fig. 22. Schematic of cell lasers for imaging source[58]
    Micro-laser source for implantable biological tissue[69]. (a) Implant in the bovine cornea; (b) implant in the blood; (c) implant in the skin tissue
    Fig. 23. Micro-laser source for implantable biological tissue[69]. (a) Implant in the bovine cornea; (b) implant in the blood; (c) implant in the skin tissue
    Mengcong Du, Qianqian Liu, Lang Marion, Xiuhong Wang, Pu Wang. Research Progress and Application of Cell Lasers[J]. Laser & Optoelectronics Progress, 2018, 55(12): 120001
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