The propagation of the (2+1)-dimensional breathers in a nematic liquid crystal (NLC) cell is theoretically investigated, whose tilt angle is fixed to π/4 in anywhere without bias voltage. The reponse function of beam′s propagation in such a special cell is obtained by the Green function which is based on a (2+1)-dimensional nonlocal nonlinear Schro?dinger equation (NNLSE), and at the same time，the nonlinear coefficient in this case is obtained. The results show that the nonlinear effects can be stronger by certain technical means. On the balance point, the potential is approximate to the 2nd order, an approximate breather solution is presented. In addition, another breather solution is obtained by numerical integration. Respectively compared the breather amplitude fluctuations, period and the maximal (minimal) widths which are calculated by the two theoretical methods with the numerical simulations, it is obviously found that the results of numerical integration are more accurate.