. Preparation routes and TEM (b,c) and SEM (c) images

. TEM images of PS@SiO₂ hybrids sphere (a-c) and HCS-1 (d-f)

. TEM images of HCS-1.5 (a-c) and HCS-0.5 (d-f), the relationship between TEOS amount and HCS thickness (g), and schematic illustration for the pyrolysis deposition of the PS inside the mesoporous silica shell (h) and the silica shell encapsulation nanoreactor (i), TGA analyses of PS and PS@SiO₂ samples in N₂ (j) and air (k)

. N₂ adsorption-desorption isotherms (a) and pore distributions (b) of HCS, XRD patterns of HCS-1 (c), XPS spectra of HCS-1 (d), C1s (e) and O1s (f) spectra of HCS-1

. SEM images of HCS with dimeter size of 400, 900 and 1600 nm obtained by changing the dimeter of PS (a-c) and N₂ adsorption-desorption isotherm (d) and pore distribution (inset) of HCS

. Adsorption curve of cefalexin over HCS-1 for the contact time (a), various initial concentrations (b), and corresponding Kinetics (c-d) and isothermal (e-f) fittings