Qi Yang, Binbin Luo, Zhipeng Gu, Shengxi Wu, Shenghui Shi, Mingfu Zhao. Graphene Oxide Microfiber-Based Immunosensor for Rabies Virus[J]. Laser & Optoelectronics Progress, 2023, 60(7): 0728004
- Laser & Optoelectronics Progress
- Vol. 60, Issue 7, 0728004 (2023)
Fig. 1. Schematic diagram of experimental system
Fig. 2. Microscopic image and spectrum of microfiber. (a) Diameter and length of microfiber;（b）interference spectrum of microfiber in water
Fig. 3. RI sensitivity calibration of microfiber. (a) Transmission spectra in different RI solutions;（b）RI sensitivity of microfiber
Fig. 4. Biofunctionalization process of microfiber
Fig. 5. FESEM photos of GO-coated microfiber. (a) 3KX; (b) 30KX
Fig. 6. Energy spectrum of microfiber surface modified with GO
Fig. 7. Spectra detection results in surface modification and functionalization of immunosensor. (a) Spectral evolution of microfiber; (b) corresponding wavelength red shift
Fig. 8. RV antibody detection experiment of immunosensor. (a) Change curves of spectrum with RV antigen concentration; (b) variation curve of resonance wavelength shift with time
Fig. 9. Relationship between wavelength red shift of microfiber immunosensor and concentration of RV antibody. (a) Langmuir curve fitting diagram; (b) detection sensitivity of microfiber immunosensor
Fig. 10. Experimental results of clinical immunodetection of microfiber immunosensors. (a) Evolution curve of spectrum; (b) changes of resonance wavelength shift
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Table 1. Elemental mass fraction of microfiber surface modified with GO
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