Shenghui Shi, Qinglin Nie, Shanghai Jiang, Shengxi Wu, bin Tang, Mingfu Zhao. Biosensor Based on Dual-Resonance Long-Period Fiber Gratings for Detection of H9N2 Subtype Avian Influenza Virus[J]. Acta Optica Sinica, 2022, 42(1): 0106001
- Acta Optica Sinica
- Vol. 42, Issue 1, 0106001 (2022)
Fig. 1. Schematic diagram of DR-LPFG modified with nano-TiO2 particles
Fig. 2. FESEM images of nano-TiO2-intergrated DR-LPFG. (a) 300×; (b) 5000×
Fig. 3. Biofunctionalization of the DR-LPFG sensor. (a) nano-TiO2 immobilization; (b) sensor surface modified with anti-H9N2 MAbs; (c) sealing of redundant binding sites
Fig. 4. Diagram of experimental system. (a) Schematic diagram; (b) experimental setup
Fig. 5. RI response of DR-LPFG sensor modified with nano-TiO2. (a) Transmission spectra evolution of the sensor versus the RI of NaCl solution; (b) RI sensitivity change of the sensor before and after nano-TiO2 coating
Fig. 6. Variation of dual-resonance spacing of the biosensor. (a) anti-H9N2 MAbs immobilization; (b) sealing of redundant binding sites with SMPSF
Fig. 7. Transmission spectra evolution of the DR-LPFG against the mass concentration of H9N2 AIV
Fig. 8. Relationship between dual-peak spacing of sensor and different parameters. (a) Different mass concentrations of H9N2 AIV solutions; (b) logarithm of different mass concentrations of H9N2 AIV solutions
Fig. 9. Variation of the dual-resonance spacing of the DR-LPFG based biosensor during the specific test
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Table 1. Others proposed biosensors for AIV detection
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