• Chinese Optics Letters
  • Vol. 16, Issue 7, 071701 (2018)
Myeongsu Seong1, Phuong Minh Mai2, Kijoon Lee3, and Jae Gwan Kim1、2、*
Author Affiliations
  • 1Department of Biomedical Science and Engineering, Institute of Integrated Technology, Gwangju Institute of Science and Technology, Gwangju 61005, Korea
  • 2School of Electrical Engineering and Computer Science, Gwangju Institute of Science and Technology, Gwangju 61005, Korea
  • 3School of Undergraduate Studies, Daegu Gyeongbuk Institute of Science and Technology, Daegu 42988, Korea
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    DOI: 10.3788/COL201816.071701 Cite this Article Set citation alerts
    Myeongsu Seong, Phuong Minh Mai, Kijoon Lee, Jae Gwan Kim. Simultaneous blood flow and oxygenation measurements using an off-the-shelf spectrometer[J]. Chinese Optics Letters, 2018, 16(7): 071701 Copy Citation Text show less

    Abstract

    Blood oxygenation and flow are both important parameters in a living body. In this Letter, we introduce a simple configuration to simultaneously measure blood flow and oxygenation using an off-the-shelf spectrometer. With the integration time of 10 ms, flow phantom measurements, a liquid blood phantom test, and an arm cuff occlusion paradigm were performed to validate the feasibility of the system. We expect this proof-of-concept study would be widely adopted by other researchers for acquiring both blood flow and oxygenation changes due to its straightforward configuration and the possibility of multimodal measurement.
    Kt(T)2=(σtIt)2=2βT0T(1τT)[g1(τ)]2dτ,(1)

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    (ΔHbΔHbO)=1d·DPF(εHbλ1εHbOλ1εHbλ2εHbOλ2)1(ΔODλ1ΔODλ2),(2)

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    g2(τ)=1+β|g1(τ)|,(3)

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    Myeongsu Seong, Phuong Minh Mai, Kijoon Lee, Jae Gwan Kim. Simultaneous blood flow and oxygenation measurements using an off-the-shelf spectrometer[J]. Chinese Optics Letters, 2018, 16(7): 071701
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