Tobacco flavours have great effect on the aroma, taste and quality stabilization of cigarettes. In order to effectively control the quality of cigarette flavours and reduce the content level of toxic elements in cigarette mainstream smoke, a method for the simultaneous determination of Be, V, Cr, Mn, Ni, Cu, Zn, As, Se, Sr, Mo, Cd, Tl and Pb in cigarette flavours by inductively coupled plasma mass spectrometry (ICP-MS ) with closed-vessel microwave assisted digestion was developed. The linear correlative coefficients for all elements are better than 0.999 4 and the precision of measurement ranges from 1.3% to 9.5% in terms of relative standard deviation(n=5). The recoveries for the cigarette flavour samples and the limits of detection are in the range of 88.1%-109.3% and 0.003-0.13 μg·L－1, respectively. The results of experiment show that the method can meet the requirements of trace analysis. Thirty eight cigarette flavours from different cigarette manufacturing enterprises were determined. The results indicate that: (1) the contents of Be, Tl, Mo, Cd, V, Pb and As in cigarette flavours are very lower, the average values of which are all lower than 0.1 μg·g-1. The content levels of Mn, Zn and Sr in cigarette flavours are higher, and that of other 4 elements are moderate. (2) The content difference of Mn, Cd and Sr in different cigarette flavours is usually bigger, the coefficients of variation of which are 276.4%, 238.7% and 243.8%, respectively.