• Laser & Optoelectronics Progress
  • Vol. 58, Issue 19, 1917001 (2021)
Liangchuang Su and Tao Chen*
Author Affiliations
  • Faculty of Materials and Manufacturing, Beijing University of Technology, Beijing 100124, China
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    DOI: 10.3788/LOP202158.1917001 Cite this Article Set citation alerts
    Liangchuang Su, Tao Chen. Wireless Stimulation System with Multiple Channels and Independent Regulation for Optogenetics in Vitro[J]. Laser & Optoelectronics Progress, 2021, 58(19): 1917001 Copy Citation Text show less
    Schematic representation of the structure of optical stimulation system
    Fig. 1. Schematic representation of the structure of optical stimulation system
    Software interface of the host computer
    Fig. 2. Software interface of the host computer
    Photo of baseplate of optrode
    Fig. 3. Photo of baseplate of optrode
    Welding process of μLED chip. (a) Photo of μLED chip; (b) μLED chip with solder paste; (c) successfully welded single μLED; (d) photo of whole optrode module
    Fig. 4. Welding process of μLED chip. (a) Photo of μLED chip; (b) μLED chip with solder paste; (c) successfully welded single μLED; (d) photo of whole optrode module
    Flowchart of program of stimulator
    Fig. 5. Flowchart of program of stimulator
    Photograph of optical stimulator and optrode
    Fig. 6. Photograph of optical stimulator and optrode
    Relationship between output optical power and distance and the number of open channel. (a) Relationship between output optical power and distance; (b) relationship between output optical power and the number of open channel
    Fig. 7. Relationship between output optical power and distance and the number of open channel. (a) Relationship between output optical power and distance; (b) relationship between output optical power and the number of open channel
    Relationship between output optical power and running time
    Fig. 8. Relationship between output optical power and running time
    Output waveforms of stimulator under different standard frequency values. (a) 1 Hz; (b) 50 Hz; (c) 250 Hz; (d) 500 Hz
    Fig. 9. Output waveforms of stimulator under different standard frequency values. (a) 1 Hz; (b) 50 Hz; (c) 250 Hz; (d) 500 Hz
    Relationship between standard frequency and output frequency or error
    Fig. 10. Relationship between standard frequency and output frequency or error
    Relationship between packet loss rate and distance of wireless communication
    Fig. 11. Relationship between packet loss rate and distance of wireless communication
    Testing of multichannel of optrode. (a) Channel 1 is open; (b) channel 2 is open; (c) channel 3 is open; (d) channel 4 is open; (e) channel 5 is open; (f) channel 6 is open; (g) channels 1,3,and 5 are open; (h) channels 2, 4, and 6 are open; (i) all channels are open
    Fig. 12. Testing of multichannel of optrode. (a) Channel 1 is open; (b) channel 2 is open; (c) channel 3 is open; (d) channel 4 is open; (e) channel 5 is open; (f) channel 6 is open; (g) channels 1,3,and 5 are open; (h) channels 2, 4, and 6 are open; (i) all channels are open
    Dominant wavelengthλ /nmChip size L×W×H /(μμμm)

    Forward current

    I /mA

    Forward voltage

    Vtyp /V

    Radiant flux

    ϕ /mW

    470270×200×50203.1521
    Table 1. Parameters of D2227 chip
    Liangchuang Su, Tao Chen. Wireless Stimulation System with Multiple Channels and Independent Regulation for Optogenetics in Vitro[J]. Laser & Optoelectronics Progress, 2021, 58(19): 1917001
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