The optical coherence tomography(OCT) technology is used to monitor the treatment of photoaged mouse skin, which is irradiated by intense plused light(IPL). A photoaged mouse skin irradiated by ultraviolet, is treated by IPL. The OCT technology is used to observe the process of the collagen remodeling in dermis. The change of optical characteristic parameter such as attenuation coefficient during the skin rejunvenation is gotten, and the magnitude of optical-thermal damage based on the changes of optical parameter is estimated. The results indicate that IPL can be used for symptoms of photoaged skin as a nonablative method, and OCT has potential as a method for characterization of collagen remodling in vivo in clinic.