• Photonics Research
  • Vol. 8, Issue 7, 1124 (2020)
Zhen Che1、†, Wenguo Zhu1、2、†, Yaoming Huang1、2, Yu Zhang1、2, Linqing Zhuo1、2, Pengpeng Fan1、2, Zhibin Li1、2, Huadan Zheng1、2, Wenjin Long1、2, Wentao Qiu1、2, Yunhan Luo1、2, Jun Zhang1、2, Jinghua Ge3, Jianhui Yu1、2、*, and Zhe Chen1、2、4
Author Affiliations
  • 1Key Laboratory of Optoelectronic Information and Sensing Technologies of Guangdong Higher Education Institutes, Guangdong Provincial Key Laboratory of Optical Fiber Sensing and Communications, Jinan University, Guangzhou 510632, China
  • 2Department of Optoelectronic Engineering, Jinan University, Guangzhou 510632, China
  • 3Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
  • 4e-mail: thzhechen@jnu.edu.cn
  • show less
    DOI: 10.1364/PRJ.388106 Cite this Article Set citation alerts
    Zhen Che, Wenguo Zhu, Yaoming Huang, Yu Zhang, Linqing Zhuo, Pengpeng Fan, Zhibin Li, Huadan Zheng, Wenjin Long, Wentao Qiu, Yunhan Luo, Jun Zhang, Jinghua Ge, Jianhui Yu, Zhe Chen. Distance-controllable and direction-steerable opto-conveyor for targeting delivery[J]. Photonics Research, 2020, 8(7): 1124 Copy Citation Text show less

    Abstract

    Opto-conveyors have attracted widespread interest in various fields because of their non-invasive and non-contact delivery of micro/nanoparticles. However, the flexible control of the delivery distance and the dynamic steering of the delivery direction, although very desirable in all-optical manipulation, have not yet been achieved by opto-conveyors. Here, using a simple and cost-effective scheme of an elliptically focused laser beam obliquely irradiated on a substrate, a direction-steerable and distance-controllable opto-conveyor for the targeting delivery of microparticles is implemented. Theoretically, in the proposed scheme of the opto-conveyor, the transverse and longitudinal resultant forces of the optical gradient force and the optical scattering force result in the transverse confinement and the longitudinal transportation of microparticles, respectively. In this study, it is experimentally shown that the proposed opto-conveyor is capable of realizing the targeting delivery for microparticles. Additionally, the delivery distance of microparticles can be flexibly and precisely controlled by simply adjusting the irradiation time. By simply rotating the cylindrical lens, the proposed opto-conveyor is capable of steering the delivery direction flexibly within a large range of azimuthal angles, from ?75° to 75°. This study also successfully demonstrated the real-time dynamic steering of the delivery direction from ?45° to 45° with the dynamical rotation of the cylindrical lens. Owing to its simplicity, flexibility, and controllability, the proposed method is capable of creating new opportunities in bioassays as well as in drug delivery.
    FL=FGL+FSL=FGL+FS×cos(θ)×cos(α),(1)

    View in Article

    FT=FGT+FST=FGT+FS×cos(θ)×sin(α).(2)

    View in Article

    E(x,y,z)=E0ω0xω0yωx(z)ωy(z)×exp{i[kzη(z)]x2[1ωx2(z)+ik2Rx(z)]y2[1ωy2(z)+ik2Ry(z)]},(3)

    View in Article

    m·ddt(dldt)FL+FD(vl)=0,(4)

    View in Article

    FD(vl)=6πηrvl,(5)

    View in Article

    ηc=η1(916)(rs)+(19)(rs)3,(6)

    View in Article

    m·ddt(dldt)FL+FD(vl)=m·ddt(dldt)FL+6πηcrvl=0.(7)

    View in Article

    Fz=FS=npcQS=npc[1+Rcos(2θ1)T2cos(2θ12θ2)+Rcos(2θ1)1+R2+2Rcos(2θ2)],(B1)

    View in Article

    Fy=FG=npcQG=npc[Rsin(2θ1)+T2sin(2θ12θ2)+Rsin(2θ1)1+R2+2Rcos(2θ2)],(B2)

    View in Article

    Zhen Che, Wenguo Zhu, Yaoming Huang, Yu Zhang, Linqing Zhuo, Pengpeng Fan, Zhibin Li, Huadan Zheng, Wenjin Long, Wentao Qiu, Yunhan Luo, Jun Zhang, Jinghua Ge, Jianhui Yu, Zhe Chen. Distance-controllable and direction-steerable opto-conveyor for targeting delivery[J]. Photonics Research, 2020, 8(7): 1124
    Download Citation