• Journal of Innovative Optical Health Sciences
  • Vol. 15, Issue 6, 2240012 (2022)
Jiyuan Xiong1, Xu Wang1, Xiaoming Hu1、*, Ying Han2、**, and Qin Li1
Author Affiliations
  • 1Key Laboratory of Convergence Medical Engineering System and Healthcare Technology, Ministry of Industry and Information Technology, School of Life Science, Beijing Institute of Technology, Beijing 100081, P. R. China
  • 2Department of Oral Medicine, Peking University School of Stomatology, Beijing 100081 P. R. China
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    DOI: 10.1142/S1793545822400120 Cite this Article
    Jiyuan Xiong, Xu Wang, Xiaoming Hu, Ying Han, Qin Li. A portable illumination device for photodynamic therapy of the oral cavity[J]. Journal of Innovative Optical Health Sciences, 2022, 15(6): 2240012 Copy Citation Text show less

    Abstract

    Photodynamic therapy (PDT) is a minimally invasive method for treating oral leukoplakia. In this paper, we propose a portable PDT device consisting of a flexible circuit board with a liquid flow cooling module on the back. The light source size was 17mm×11mm×4mm, and the irradiation area of the light source was up to 100mm2. The irradiance range of this device was from 10mW/cm2 to 100mW/cm2. Simulation and experimental results showed that the irradiance coefficient variation for a treatment area of 81mm2 was less than 7%. At an irradiance of 100mW/cm2, a device surface temperature of lower than 42C can be achieved to satisfy the safety requirements under the conditions that the temperature of cooling liquid is 10C and the liquid flow speed is above 12mL/min.Photodynamic therapy (PDT) is a minimally invasive method for treating oral leukoplakia. In this paper, we propose a portable PDT device consisting of a flexible circuit board with a liquid flow cooling module on the back. The light source size was 17mm×11mm×4mm, and the irradiation area of the light source was up to 100mm2. The irradiance range of this device was from 10mW/cm2 to 100mW/cm2. Simulation and experimental results showed that the irradiance coefficient variation for a treatment area of 81mm2 was less than 7%. At an irradiance of 100mW/cm2, a device surface temperature of lower than 42C can be achieved to satisfy the safety requirements under the conditions that the temperature of cooling liquid is 10C and the liquid flow speed is above 12mL/min.