• Journal of Innovative Optical Health Sciences
  • Vol. 15, Issue 1, 2242001 (2022)
[in Chinese]1、2, [in Chinese]1, [in Chinese]3, [in Chinese]3, [in Chinese]3, [in Chinese]4, [in Chinese]5, [in Chinese]6, [in Chinese]1, [in Chinese]1、2, [in Chinese]1、2, and [in Chinese]1、2、*
Author Affiliations
  • 1School of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao, Hebei 066004, P. R. China
  • 2Hebei Key Laboratory of Micro-Nano Precision, Optical Sensing and Measurement Technology, Qinhuangdao, Hebei 066004, P. R. China
  • 3Department of Ophthalmology, The First Hospital of Qinhuangdao, Qinhuangdao, Hebei 066004, P. R. China
  • 4Department of Ophthalmology, Qinhuangdao Maternal and Child Health Hospital, Qinhuangdao, Hebei 066004, P. R. China
  • 5Tangshan Maternal and Children Hospital, Tangshan, Hebei 063000, P. R. China
  • 6Biomedical Information Engineering Lab, The University of Aizu, Aizu-Wakamatsu, Fukushima 965-8580, Japan
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    DOI: 10.1142/s1793545822420019 Cite this Article
    [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese]. Automatic segmentation of foveal avascular zone based on adaptive watershed algorithm in retinal optical coherence tomography angiography images[J]. Journal of Innovative Optical Health Sciences, 2022, 15(1): 2242001 Copy Citation Text show less

    Abstract

    The size and shape of the foveal avascular zone (FAZ) have a strong positive correlation with several vision-threatening retinovascular diseases. The identification, segmentation and analysis of FAZ are of great significance to clinical diagnosis and treatment. We presented an adaptive watershed algorithm to automatically extract FAZ from retinal optical coherence tomography angiography (OCTA) images. For the traditional watershed algorithm, "over-segmentation" is the most common problem. FAZ is often incorrectly divided into multiple regions by redundant "dams". This paper analyzed the relationship between the "dams" length and the maximum inscribed circle radius of FAZ, and proposed an adaptive watershed algorithm to solve the problem of "over-segmentation". Here, 132 healthy retinal images and 50 diabetic retinopathy (DR) images were used to verify the accuracy and stability of the algorithm. Three ophthalmologists were invited to make quantitative and qualitative evaluations on the segmentation results of this algorithm. The quantitative evaluation results show that the correlation coefficients between the automatic and manual segmentation results are 0.945 (in healthy subjects) and 0.927 (in DR patients), respectively. For qualitative evaluation, the percentages of "perfect segmentation" (score of 3) and "good segmentation" (score of 2) are 99.4% (in healthy subjects) and 98.7% (in DR patients), respectively. This work promotes the application of watershed algorithm in FAZ segmentation, making it a useful tool for analyzing and diagnosing eye diseases.
    [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese]. Automatic segmentation of foveal avascular zone based on adaptive watershed algorithm in retinal optical coherence tomography angiography images[J]. Journal of Innovative Optical Health Sciences, 2022, 15(1): 2242001
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