In order to decompose and transform the toxic refractory typical pollutants from ABS resin wastewater, this wastewater was pretreated by the micro-electrolysis. The decomposition and transformation of the typical pollutants from ABS wastewater was detected by Fourier transform infrared (FTIR). The results show that those typical pollutants, such as acrylonirile, styrene, alpha, alpha-dimethyl-benzenemethanol, acetophenone, 3,3′-oxybis-propanenitrile and 3,3′-iminobis-propanenitrile, could be decomposed and transformed by the micro-electrolysis under the condition of the influent pH value of 4.0. The degradation products of those typical pollutants were small molecule organic compounds such as unsaturated fatty acids, alcohols or acylamides. And the BOD/COD ratio of ABS resin wastewater was increased from 0.32 to 0.71 after the treatment of micro-electrolysis, in other words, the biodegradability of ABS resin wastewater was increased significantly.