Investigation has been carried out into the solidifying like-waste nuclear materials borosilicate by laser glassing. The results showed that laser glassing related to the laser power, scanning speed and laser beam diameter. The quantity variation of vitrification can be described using two parameters of laser power density and scanning speed. For example, when laser power density is the order of 25.48 W/nim2, scanning speed is at 8 mm/s, the volume of laser glassing can be reached the value of 532.0 mm3/s. The microscopical analysis indicated that laser irradiating region consisted of vitreous body, transition zone, sinter and original powder region when powders were put in advance during laser glassing process. The elements Na, B, Si, Ο were homogeneously distributed in vitreous body, and there didn't exist crystal phases.