In this paper, a programmable method of laser pulse selection and amplitude control is proposed to generate pulse bursts with arbitrary time-domain waveform. A flexible and programmable pulse picker unit based on field-programmable gate array is used to drive the acousto-optic modulator to realize the fine control of each pulse's energy in bursts. Based on this innovative regulation technology of pulses' time-domain characteristics, high-energy bursts with different time-domain waveforms are realized by using ytterbium-doped chirped pulse fiber amplification system. The outputs of the system are the bursts with burst energy of 20 μJ, burst repetition rate of 1 MHz, and pulse width of less than 300 fs.