• Journal of Innovative Optical Health Sciences
  • Vol. 16, Issue 6, 2340006 (2023)
Lanlan Li1, Jing Qi1, Yi Geng1, and Jingpeng Wu2,*
Author Affiliations
  • 1Fujian Key Lab for Intelligent Processing and Wireless Transmission of Media Information, College of Physics and Information Engineering, Fuzhou University, Fuzhou, Fujian 350116, P. R. China
  • 2Center for Computational Neuroscience, Flatiron Institute, New York 10010, USA
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    DOI: 10.1142/S1793545823400060 Cite this Article
    Lanlan Li, Jing Qi, Yi Geng, Jingpeng Wu. Semantic segmentation of pyramidal neuron skeletons using geometric deep learning[J]. Journal of Innovative Optical Health Sciences, 2023, 16(6): 2340006 Copy Citation Text show less

    Abstract

    Neurons can be abstractly represented as skeletons due to the filament nature of neurites. With the rapid development of imaging and image analysis techniques, an increasing amount of neuron skeleton data is being produced. In some scientific studies, it is necessary to dissect the axons and dendrites, which is typically done manually and is both tedious and time-consuming. To automate this process, we have developed a method that relies solely on neuronal skeletons using Geometric Deep Learning (GDL). We demonstrate the effectiveness of this method using pyramidal neurons in mammalian brains, and the results are promising for its application in neuroscience studies.

    Lanlan Li, Jing Qi, Yi Geng, Jingpeng Wu. Semantic segmentation of pyramidal neuron skeletons using geometric deep learning[J]. Journal of Innovative Optical Health Sciences, 2023, 16(6): 2340006
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