The intravascular ultrasound (IVUS) and the intravascular optical coherence tomography (OCT) both belong to the non-invasive medical imaging techniques, which are often used for the examination of thin cap fibroatheromas (TCFA) in the human coronary arteries. The detection depth of IVUS is large, so the size of TCFA can be measured accurately, but due to the lower resolution, the fiber cap thickness of TCFA cannot be measured, whereas the OCT has high resolution, which enables it to accurately measure the thickness of the TCFA, but it cannot describe the size of TCFA because of small detection depth. By combining IVUS with OCT, ultrasound and OCT tomographic images of the vascular wall can be obtained simultaneously in a single examination, and the accurate diagnosis of intravascular thrombosis and plaque is achieved. In this paper, we design and realize IVUS and OCT integrated micro-scanning probe and near-end driving module. Meanwhile, a set of system that can simultaneously perform IVUS and OCT imaging on the blood vessel wall is realized. The detection depth of the blood vessel tissue reaches 8 mm, the lateral resolution is better than 1 mm, the axial resolution is better than 400 μm, the lateral resolution is better than 10 μm and the axial resolution is better than 8 μm in the 1 mm range. Vascular models are built with agar and wire, and imaging experiments are performed to verify the feasibility of the system.