Fig. 1. Flow chart of SQP
Fig. 2. Flow chart of step acceleration algorithm
Fig. 3. Time-domain infrared radiative signal measurement system based on TCSPC
Fig. 4. Principle diagram of time-domain infrared signal measurement
Fig. 5. Comparison of simulated signals and measured signals for phantoms. (a) Phantom 1; (b) phantom 2
Fig. 6. Influence of laser power on measured curve
Fig. 7. Model with fiber setup
Fig. 8. Reconstructed results of absorption coefficient and scattering coefficient. (a)(d) Without measurement error; (b)(e) with 3% measurement error; (c)(f) with 5% measurement error
Fig. 9. Medium models for simulating cancerous tissues. (a) Skin tissue; (b) liver tissue
Fig. 10. Reconstruction results of skin tissue containing tumour. (a) Absorption coefficient; (b) scattering coefficient
Fig. 11. Reconstruction results of liver tissue containing tumour. (a) Absorption coefficient; (b) scattering coefficient
Parameter | Background medium | Inclusion A | Inclusion B |
---|
/cm-1 | 0.5 | 0.1 | 1.0 | /cm-1 | 1.0 | 0.5 | 1.5 |
|
Table 1. Real distributions of optical parameters in medium
Case | /cm-1 | /cm-1 |
---|
Case 1 | 0.1 | 0.5 | Case 2 | 0.5 | 1.0 | Case 3 | 1.5 | 2.0 | Case 4 | 3.5 | 4.0 |
|
Table 2. Choice of initial value
Case | /cm-1 | /cm-1 |
---|
Case 1 | 0.13677 | 0.14156 | Case 2 | 0.12764 | 0.10635 | Case 3 | 0.19440 | 0.11756 | Case 4 | Misconvergence | Misconvergence |
|
Table 3. ENRMSE of reconstruction results
Initial value /cm-1 | Search result |
---|
/cm-1 | /cm-1 |
---|
0.01 | 0.50179 | 0.99303 | 0.10 | 0.50180 | 0.99325 | 1.00 | 0.50188 | 0.99280 | 10.00 | 0.50187 | 0.99268 | 100.00 | 0.50188 | 0.99303 |
|
Table 4. Search results of step acceleration algorithm
Coefficient | Skin | Liver |
---|
Normal | Tumour | | Normal | Tumour |
---|
/cm-1 | 0.15 | 0.06 | 1.00 | 0.60 | /cm-1 | 75.00 | 15.80 | 204.00 | 108.00 |
|
Table 5. Absorption and scattering coefficients of human skin tissue[29] and liver tissue[30]