In order to study the effect of different process parameters on the residual stress in laser additive manufacturing, 10 test samples are made with different process parameters by the special laser additive manufacturing system with TA15 alloy material. Cross sectiions of specimens are all 24 mm×40 mm square. Using the indentation stress measurement method to measure the residual stress of sample, laser power density and powder flow density on the residual stress in laser additive manufacturing are studied. The results show that the residual stress in the laser additive manufacturing is significantly less than the yield strength. The residual stress is positively correlated with the laser specific energy and laser power density, and is negatively correlated with the powder flow density.