Directional polarization camera (DPC) is a space remote sensor with multi-spectrum, multi-angle and multi-polarization data. The procedure of laboratory geometric calibration is complex and it needs to process a large amount of data. By analyzing the principle, model and flow of the DPC laboratory geometric calibration and discussing the demand and framework of the software, we develop a flow-based data-processing software. The software is able to pre-process various calibration test data of the original image and calculate various scaling parameters rapidly. Compared with the manual calculation time of 40 min, the data processing software costs only 50 s. In conclusion, the software can meet the real-time requirement of laboratory calibration.