• Spectroscopy and Spectral Analysis
  • Vol. 42, Issue 9, 2818 (2022)
Song-tao CAI1、*, Hua-lin XIE2、2;, and Jian-hua HUANG3、3; *;
Author Affiliations
  • 11. College of Materials Science and Engineering, Hunan Institute of Technology, Hengyang 421002, China
  • 22. College of Chemistry and Chemical Engineering, Yangtze Normal University, Chongqing 408100, China
  • 33. Institute of Chinese Materia Medica, Hunan Academy of Traditional Chinese Medicine, Changsha 410013, China
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    DOI: 10.3964/j.issn.1000-0593(2022)09-2818-06 Cite this Article
    Song-tao CAI, Hua-lin XIE, Jian-hua HUANG. Analysis of Heavy Metal Cd in Cereal-Based Complementary Foods for Infants and Young Children by Inductively Coupled Plasma Tandem Mass Spectrometry (ICP-MS/MS)[J]. Spectroscopy and Spectral Analysis, 2022, 42(9): 2818 Copy Citation Text show less
    The mass spectrums of mixed standard solution (100 μg·L-1 Mo+1 μg·L-1 Sn+1 μg·L-1 Cd) in (a) H2 reaction mode and (b) NH3/He reaction mode
    Fig. 1. The mass spectrums of mixed standard solution (100 μg·L-1 Mo+1 μg·L-1 Sn+1 μg·L-1 Cd) in (a) H2 reaction mode and (b) NH3/He reaction mode
    The mass spectrums of mixed standard solution (100 μg·L-1 Mo+1 μg·L-1 Sn+1 μg·L-1 Cd) in O2 reaction mode
    Fig. 2. The mass spectrums of mixed standard solution (100 μg·L-1 Mo+1 μg·L-1 Sn+1 μg·L-1 Cd) in O2 reaction mode
    Effect of O2 flow rate on the determination of Cd in standard reference material SRM 1568b
    Fig. 3. Effect of O2 flow rate on the determination of Cd in standard reference material SRM 1568b
    The mass spectrum of 1 μg·L-1 Rh standard solution in O2 reaction mode
    Fig. 4. The mass spectrum of 1 μg·L-1 Rh standard solution in O2 reaction mode
    IsotopeAbundance
    /%
    ModeInterfering ionProductionBEC/(ng·L-1)
    H2NH3/HeO2
    110Cd12.49On-mass98Mo12C+, 97Mo13C+, 96Mo14N+, 94Mo16O+110Cd+36.515.87.52
    111Cd12.80On-mass98Mo13C+, 96Mo14N+, 95Mo16O+111Cd+30.99.703.06
    112Cd24.13On-mass100Mo12C+, 98Mo14N+, 96Mo16O+, 112Sn+112Cd+51.523.615.1
    113Cd12.22On-mass100Mo13C+, 97Mo16O+113Cd+40.311.76.03
    114Cd28.73On-mass100Mo14N+, 98Mo16O+, 114Sn+114Cd+55.231.418.9
    116Cd7.49On-mass100Mo16O+, 116Sn+116Cd+16253.026.4
    Table 1. Background equivalent concentration (BEC) obtained for Cd by using different reaction gases
    IsotopeLinear range
    /(μg·L-1)
    Correlation
    coefficient (R)
    LOD
    /(ng·L-1)
    110Cd0.012~101.000 05.16
    111Cd0.004~100.999 92.03
    112Cd0.016~100.999 811.8
    113Cd0.008~101.000 04.70
    114Cd0.020~100.999 913.4
    Table 2. Linear relationship and limits of detection (LODs) for Cd isotopes
    Standard reference materialCertified
    /(μg·kg-1)
    Found/(μg·kg-1)t test
    This methodGB5009.268—2016
    Rice flour (SRM 1566a)22.4±1.322.1±1.022.7±1.6p=0.23
    Liaoning rice (GBW10043)12.0±3.011.6±0.711.8±1.2p=0.37
    Sichuan rice (GBW10044)18.0±2.018.4±0.618.7±0.8p=0.24
    Hunan rice (GBW10045)190±20186±11.3193±14.1p=0.18
    Table 3. Analysis results of standard reference material (n=6)
    SampleOriginThis methodGB5009.268—2016
    Found/(μg·kg-1)RSD/%Found/(μg·kg-1)RSD/%
    Millet flour for infantsJiangxi7.26±0.314.37.19±0.365.0
    Organic millet flour for infantsSichuan5.12±0.193.75.20±0.234.4
    Millet flour for infantsShanxi3.38±0.103.03.31±0.123.6
    Rice flour for infantsShanghai6.05±0.213.55.97±0.183.0
    Chicken mushroom porridgeJapan2.43±0.062.52.48±0.114.4
    Salmon corn porridgeJapan2.08±0.073.42.03±0.083.9
    Table 4. Analysis results of Cd content in cereal food for infants (n=6)
    Song-tao CAI, Hua-lin XIE, Jian-hua HUANG. Analysis of Heavy Metal Cd in Cereal-Based Complementary Foods for Infants and Young Children by Inductively Coupled Plasma Tandem Mass Spectrometry (ICP-MS/MS)[J]. Spectroscopy and Spectral Analysis, 2022, 42(9): 2818
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