Zhong Chen, Guangbin Shang, Liu Fu, Ge Liu, Xuan Chen, Qi Zhang, Xiaonan Lu. Transcriptome Characteristics Analysis of Terahertz Wave Inhibited Leukemia K562 Cells Based on RNA Sequencing[J]. Laser & Optoelectronics Progress, 2022, 59(7): 0717001
- Laser & Optoelectronics Progress
- Vol. 59, Issue 7, 0717001 (2022)
Fig. 1. Effect of terahertz wave on K562 cell viability
Fig. 2. Correlation analysis of samples. (a) Correlation between expressed genes of the blank control group and the intervention group; (b) PCA result of expressed genes of the blank control group and the intervention group
Fig. 3. Changes of genes in K562 cells after terahertz wave intervention. (a) Volcano plot of differentially expressed genes; (b) heatmap of top 50 differentially expressed genes by |log2(XFC)|
Fig. 4. Terahertz wave interferes with GO function of K562 cells differentially expressed genes. (a) Up-regulated differentially expressed genes; (b) down-regulated differentially expressed genes
Fig. 5. GO enrichment analysis of K562 up-regulated differentially expressed genes by terahertz wave intervention
Fig. 6. GO enrichment analysis of K562 down-regulated differentially expressed genes by terahertz wave intervention
Fig. 7. KEGG pathway enrichment analysis of differentially expressed genes in K562 cells by terahertz wave intervention. (a) Up-regulated differentially expressed genes; (b) down-regulated differentially expressed genes
Fig. 8. KEGG pathway enrichment chord diagram for differentially expressed genes. (a) Up-regulated differentially expressed genes; (b) down-regulated differentially expressed genes
Fig. 9. Core network of protein-protein interactions of differentially expressed genes in K562 cells by terahertz wave intervention
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Table 1. Quality assessment of the sequencing data
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