• Chinese Journal of Lasers
  • Vol. 45, Issue 2, 207025 (2018)
Wu Yutong1、*, Jia Mengyu1, Wang Bingyuan1, Zhao Huijuan1、2, and Gao Feng1、2
Author Affiliations
  • 1[in Chinese]
  • 2[in Chinese]
  • show less
    DOI: 10.3788/CJL201845.0207025 Cite this Article Set citation alerts
    Wu Yutong, Jia Mengyu, Wang Bingyuan, Zhao Huijuan, Gao Feng. Simulation Study on Methodological Feasibility of Diffuse Raman Tomography[J]. Chinese Journal of Lasers, 2018, 45(2): 207025 Copy Citation Text show less
    Flow chart of the DRT algorithm based on RMC generator
    Fig. 1. Flow chart of the DRT algorithm based on RMC generator
    Phantom model. (a) Three-dimensional geometry; (b) source-detector configuration
    Fig. 2. Phantom model. (a) Three-dimensional geometry; (b) source-detector configuration
    Simulated results of the heterogeneous model provided by the RMC simulator under different integration times
    Fig. 3. Simulated results of the heterogeneous model provided by the RMC simulator under different integration times
    Multi-wavelength DRT reconstruction results under the three measuring time
    Fig. 4. Multi-wavelength DRT reconstruction results under the three measuring time
    SRM of the multi-wavelength reconstruction results under the three measuring time
    Fig. 5. SRM of the multi-wavelength reconstruction results under the three measuring time
    Reconstructed three-dimensional RC distributions of the five components. (a) Lipid; (b) protein; (c) DNA; (d) B-carotene;(e) calcification
    Fig. 6. Reconstructed three-dimensional RC distributions of the five components. (a) Lipid; (b) protein; (c) DNA; (d) B-carotene;(e) calcification
    TissueExcitation /785 nmRaman /840 nmOther
    μxa /mm-1μxs /mm-1μma /mm-1μms /mm-1ngd /mm
    Epidermis0.19018.9000.13017.6001.40.80.4
    Dermis0.13011.6000.10010.6001.40.81.6
    Subcutaneous0.12011.6000.0979.7001.40.82.0
    Table 1. Optical properties of the background and the target
    MaterialLipidProteinDNAB-caroteneCalcificationμr /10-9
    CR-TCR-B0.40∶0.100.50∶0.800.30∶0.100.20∶0.020.06∶0.602.05∶3.96
    Table 2. RC of the background and target components
    MaterialLipidProteinDNAB-caroteneCalcificationμr /10-9Average
    CR-TCR-B0.400∶0.1000.500∶0.8000.300∶0.1000.200∶0.0020.006∶0.6002.051∶3.967Na
    CR-TDRTCR-BDRT0.400∶0.1700.500∶0.7300.300∶0.1730.200∶0.0470.006∶0.4802.048∶2.978Na
    RE /%23.3023.3025.0022.5020.0051.7022.82
    Table 3. RE of the reconstructed RC distributions of the five components
    Wu Yutong, Jia Mengyu, Wang Bingyuan, Zhao Huijuan, Gao Feng. Simulation Study on Methodological Feasibility of Diffuse Raman Tomography[J]. Chinese Journal of Lasers, 2018, 45(2): 207025
    Download Citation