Xuan TIAN, Shuquan FEI, Runze LI, Tong PENG, Junwei MIN, Siying WANG, Yuge XUE, Chen BAI, Baoli YAO. Artificial-intelligent quantitative phase imaging: from physics to algorithm and back to physics (inner cover paper·invited)[J]. Infrared and Laser Engineering, 2025, 54(2): 20240490

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- Infrared and Laser Engineering
- Vol. 54, Issue 2, 20240490 (2025)

Fig. 1. Classification of quantitative phase imaging techniques
![Description of dataset-driven network phase reconstruction[6]. (a) Dataset collection; (b) Network training; (c) Prediction via a well-trained network](/richHtml/irla/2025/54/2/20240490/img_2.jpg)
Fig. 2. Description of dataset-driven network phase reconstruction[6]. (a) Dataset collection; (b) Network training; (c) Prediction via a well-trained network

Fig. 3. Different network architectures and different training strategies for deep learning in phase reconstruction
![Structure of the generative adversarial network for reconstructing quantitative phase images in off-axis DH[58]](/Images/icon/loading.gif)
Fig. 4. Structure of the generative adversarial network for reconstructing quantitative phase images in off-axis DH[58]

Fig. 5. Two strategies of physical cascading networks
![CTF-Deep phase reconstruction principle and experimental results[87]. (a) CTF-Deep phase reconstruction principle; (b) Phase step experimental imaging results, and compared with other methods](/Images/icon/loading.gif)
Fig. 6. CTF-Deep phase reconstruction principle and experimental results[87]. (a) CTF-Deep phase reconstruction principle; (b) Phase step experimental imaging results, and compared with other methods
![Physics-enhanced deep neural network phase reconstruction method[6]. (a) Untrained network solution; (b) Trained network solution](/Images/icon/loading.gif)
Fig. 7. Physics-enhanced deep neural network phase reconstruction method[6]. (a) Untrained network solution; (b) Trained network solution
![Schematic diagram of dual-wavelength digital holographic imaging based on untrained neural network[100]](/Images/icon/loading.gif)
Fig. 8. Schematic diagram of dual-wavelength digital holographic imaging based on untrained neural network[100]
![The method of physics-informed neural network[113]. (a) Overview of the MaxwellNet network; (b) Tomographic reconstruction results of three-dimensional refractive index of polystyrene microspheres immersed in water using MaxwellNet and compared with Rytov prediction results](/Images/icon/loading.gif)
Fig. 9. The method of physics-informed neural network[113]. (a) Overview of the MaxwellNet network; (b) Tomographic reconstruction results of three-dimensional refractive index of polystyrene microspheres immersed in water using MaxwellNet and compared with Rytov prediction results
![Application of quantitative phase imaging in biological microscopy. (a) Phase imaging results of the internal structure of red blood cells[58]; (b) Phase imaging results of various phytoplankton and zooplankton[116]; (c) Observation of the division process of HeLa cells[115]; (d) Effects of increased oxidative stress on sperm cells[117]](/Images/icon/loading.gif)
Fig. 10. Application of quantitative phase imaging in biological microscopy. (a) Phase imaging results of the internal structure of red blood cells[58]; (b) Phase imaging results of various phytoplankton and zooplankton[116]; (c) Observation of the division process of HeLa cells[115]; (d) Effects of increased oxidative stress on sperm cells[117]
![Applications of AI-QPI in industrial measurements. (a) Measurements of the radius (ap) and refractive index (np) of a mixture of four monodisperse populations of polystyrene and silica spheres[120]; (b) Measurement of microlens arrays[51]; (c) Measurement of alcohol droplet evaporation by DL-SRQPI[115]](/Images/icon/loading.gif)
Fig. 11. Applications of AI-QPI in industrial measurements. (a) Measurements of the radius (ap ) and refractive index (np ) of a mixture of four monodisperse populations of polystyrene and silica spheres[120]; (b) Measurement of microlens arrays[51]; (c) Measurement of alcohol droplet evaporation by DL-SRQPI[115]
![Multi-prior physics enhanced neural network and imaging results[102]. (a) The structure of multi-prior physics enhanced neural network; (b) Large FOV and high-resolution phase imaging results of the phase resolution plate](/Images/icon/loading.gif)
Fig. 12. Multi-prior physics enhanced neural network and imaging results[102]. (a) The structure of multi-prior physics enhanced neural network; (b) Large FOV and high-resolution phase imaging results of the phase resolution plate
![Description of phase unwrapping method based on deep learning[133]. (a) Deep-learning-performed regression method. (b) Deep-learning-performed wrap count method; (c) Deep-learning-assisted denoising method](/Images/icon/loading.gif)
Fig. 13. Description of phase unwrapping method based on deep learning[133]. (a) Deep-learning-performed regression method. (b) Deep-learning-performed wrap count method; (c) Deep-learning-assisted denoising method
![Phase aberration correction method based on deep learning. (a) Description of the segmentation-based aberration correction method[6]; (b) Comparison of the results of SSCNet and other phase aberration compensation methods[148]](/Images/icon/loading.gif)

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