• Laser & Optoelectronics Progress
  • Vol. 59, Issue 8, 0810004 (2022)
Zhenzhen Wan1, Shuai Han1, Ning Shi2、*, Fang Liu3、4, Shaoyong Zhang1, and Chunxue Li1
Author Affiliations
  • 1College of Electronic Information Engineering, Hebei University, Baoding , Hebei 071002, China
  • 2Hebei Software Institute, Baoding , Hebei 071000, China
  • 3Baoding Children's Hospital, Baoding , Hebei 071000, China
  • 4Key Laboratory of Clinical Research on Children's Respiratory Digestive Diseases in Baoding City, Baoding , Hebei 071000, China
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    DOI: 10.3788/LOP202259.0810004 Cite this Article Set citation alerts
    Zhenzhen Wan, Shuai Han, Ning Shi, Fang Liu, Shaoyong Zhang, Chunxue Li. Computer-Aided Prognosis Evaluation for MKI of Pathological Slices of Peripheral Neuroblastic Tumors[J]. Laser & Optoelectronics Progress, 2022, 59(8): 0810004 Copy Citation Text show less
    Classification of pNT pathological images
    Fig. 1. Classification of pNT pathological images
    YCbCr and gradient amplitude diagram. (a) Original sample image; (b) YCbCr space image; (c) edge detection graph; (d) gradient amplitude image
    Fig. 2. YCbCr and gradient amplitude diagram. (a) Original sample image; (b) YCbCr space image; (c) edge detection graph; (d) gradient amplitude image
    Characteristic diagram of NEU nuclear fission
    Fig. 3. Characteristic diagram of NEU nuclear fission
    Mathematical morphology reconstruction of NEU. (a) Binary image; (b) mathematical morphology reconstruction
    Fig. 4. Mathematical morphology reconstruction of NEU. (a) Binary image; (b) mathematical morphology reconstruction
    Mathematical morphology marking and correction. (a) Mathematical morphology marking; (b) Euclidean distance transformation; (c) gradient reconstruction
    Fig. 5. Mathematical morphology marking and correction. (a) Mathematical morphology marking; (b) Euclidean distance transformation; (c) gradient reconstruction
    Effect diagrams of pNT segmentation. (a) Overlay of original images on edge of objects; (b) overlay of original images by mark matrix
    Fig. 6. Effect diagrams of pNT segmentation. (a) Overlay of original images on edge of objects; (b) overlay of original images by mark matrix
    Comparison of chromaticity characteristic components. (a) PMN; (b) interstitial space; (c) NEU; (d) Y component comparison; (e) Cb component comparison; (f) Cr component comparison
    Fig. 7. Comparison of chromaticity characteristic components. (a) PMN; (b) interstitial space; (c) NEU; (d) Y component comparison; (e) Cb component comparison; (f) Cr component comparison
    PMN extraction. (a) Threshold classification; (b) corrosion and expansion; (c) superimposed mark on original image
    Fig. 8. PMN extraction. (a) Threshold classification; (b) corrosion and expansion; (c) superimposed mark on original image
    NEU frequency distribution histogram
    Fig. 9. NEU frequency distribution histogram
    Comparison of improved watershed algorithm and doctor count
    Fig. 10. Comparison of improved watershed algorithm and doctor count
    Comparison of MKI values calculated by proposed algorithm and doctor’s manual calculation
    Fig. 11. Comparison of MKI values calculated by proposed algorithm and doctor’s manual calculation
    Cell imageIdentification by proposed algorithmIdentification by doctorNEU analysisPMN errorMKI error /%
    NEUPMNMKI /%NEUPMNMKI /%Accuracy rate /%Over divided rate /%
    152520.3850330.6095.62.14-10.22
    2648152.31605162.6492.93.43-10.33
    342010.2439110.2692.63.5800.02
    428210.3626710.3894.42.7300.02
    539620.5137220.5493.53.1200.03
    610710.9410110.9994.12.8800.05
    754830.5552920.3896.41.761-0.17
    839510.2537210.2793.82.9900.02
    931161.9329651.6994.92.471-0.24
    Table 1. Results of experiment data of pNT pathological slice image segmentation
    Zhenzhen Wan, Shuai Han, Ning Shi, Fang Liu, Shaoyong Zhang, Chunxue Li. Computer-Aided Prognosis Evaluation for MKI of Pathological Slices of Peripheral Neuroblastic Tumors[J]. Laser & Optoelectronics Progress, 2022, 59(8): 0810004
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