An inversion algorithm based on the global search (GS) is proposed for the inversion of particle size distribution (PSD) from image dynamic light scattering (IDLS) data by image correlation. The inversion for unimodal particles and bimodal particles is simulated. The peak value and particle distribution index (PDI) of unimodal particles are 79 nm and 10%, respectively. The peak values of bimodal particles are 79 nm and 352 nm with PDI of 10%. It is shown that GS inverts PSD for IDLS data successfully. Based on the simulation, the experimental inversion of unimodal particles with peak value of 79 nm and bimodal particles with peak values of 79 nm and 352 nm, 79 nm and 482 nm is performed. Compared with the cumulants method for unimodal particles and the double exponential method for bimodal particles, GS algorithm can invert PSDs of unimodal and bimodal particles successfully, which indicates that GS is an effective inversion algorithm.