LED can provide both illumination and data communication in indoor visible light communication (VLC). LED layout plays an important role in maintaining stable optical power distribution on receiving plane. LED rectangular layout can not provide a full coverage on the receiving plane in which receiving optical power interruption area exists, and can not achieve optimal performance of VLC system. Layouts of LED at different positions considering the first reflection of each wall and floor are studied. LED layouts are analyzed by particle swarm optimization (PSO) algorithm, and a LED circular layout with optimal energy consumption is designed. Rectangular layout and circular layout of LEDs are analyzed through simulation of the received optical power distribution, signal interruption rate, energy consumption and signal noise ratio distribution. The results show that, for the VLC system, the performance of the LED circular layout is better than that of the LED rectangular layout, and the LED circular layout can reduce the inter symbol interference with almost half number of LEDs used in the LED rectangular layout.