Wavelength Division Multiplexed (WDM) system characteristics using various dispersion compensation schemes are compared by computer simulation. In our model, eight 10 Gb/s WDM channels with channel spacing of 100 GHz are transmitted through cascaded optical amplifiers. Fiber dispersion, self-phase modulation (SPM), cross-phase modulation (XPM) and four-wave-mixing (FWM) effects are considered. Dispersion compensation schemes include: conventional single mode fiber (SMF)+dispersion compensating fiber with positive dispersion slope (DCF1), SMF+dispersion compensating fiber with negative dispersion slope (DCF2), non-zero dispersion fiber with positive dispersion (TW1)+non-zero dispersion fiber with nagetive dispersion (TW2) and TW2+TW1. It is shown that TW2+TW1 has the best performance, where SPM, XPM and FWM are roughly equal. On the other hand, SMF+DCF1 results in the worst performance, where the combination of dispersion and SPM effect dominates, and the shorter wavelength channels suffer from severe pulse distortion.