Surface Plasmon Resonance Sensing Technology is Applied to Small Molecule Detection

Xue-mei LIU; Xiao-lin WANG; Zeng-feng QIU; Ya-dong WANG; Bin ZHANG; Chao XU; Hong-zong YIN

doi:10.3964/j.issn.1000-0593(2021)02-0511-06

Journals >Spectroscopy and Spectral Analysis >Volume 41 >Issue 2 >Page 511 > Article

Spectroscopy and Spectral Analysis
Vol. 41, Issue 2, 511 (2021)

Surface Plasmon Resonance Sensing Technology is Applied to Small Molecule Detection

Xue-mei LIU^*, Xiao-lin WANG, Zeng-feng QIU, Ya-dong WANG, Bin ZHANG, Chao XU, and Hong-zong YIN

Author Affiliations

College of Chemistry and Materials Science, Shandong Agricultural University, Tai’an 271018, China

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DOI: 10.3964/j.issn.1000-0593(2021)02-0511-06 Cite this Article

Xue-mei LIU, Xiao-lin WANG, Zeng-feng QIU, Ya-dong WANG, Bin ZHANG, Chao XU, Hong-zong YIN. Surface Plasmon Resonance Sensing Technology is Applied to Small Molecule Detection[J]. Spectroscopy and Spectral Analysis, 2021, 41(2): 511 Copy Citation Text

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(a) Schematic diagram of FT-SPR biosensor; (b) Schematic diagram of resonance displacement of reflection spectrum; (c) Schematic diagram of SPR signal changing with time

Fig. 1. (a) Schematic diagram of FT-SPR biosensor; (b) Schematic diagram of resonance displacement of reflection spectrum; (c) Schematic diagram of SPR signal changing with time

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Fig. 2. (a) Direct detection method image, (b) Sandwich method image, (c) immunosuppression image, (d) competitive immunoassay image

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Fig. 3. Image of molecular imprinting

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检测方法		检测物质	检出限	年份, 文献
免疫传感器	直接检测法	四环素	0.006 9 μg·kg^-1	2018 [12]
		Pb(Ⅱ)离子	1.353 5×10^-6 nm	2018 [13]
		百草枯(PQ)	2.2 pmol·L^-1	2018 [14]
		腺苷	0.21 pmol·L^-1	2015 [15]
		河豚毒素	0.43 mg·kg^-1	2015 [17]
		赭曲霉素A	0.06 ng·mL^-1	2011 [18]
	“三明治”法	短寡核苷酸	0.1 fmol·L^-1	2017 [25]
		孕酮	5 nmol·L^-1	2016 [26]
		多巴胺	500 pg·mL^-1	2014 [27]
	抑制法	E2(类固唇激素)	0.3 pmol·L^-1	2018 [30]
	竞争法	叶酸(FA)	2.9 nmol·L^-1	2017 [33]
		黄曲霉毒素B1 (AFB1)	2.51 μg·L^-1	2018 [34]
		氨苄青霉素	0.003 7 ng·mL^-1	2016 [35]
		睾酮	-4.6 nm·(ng·mL^-1)^-1	2013 [36]
		苯并[a]芘和2-羟基联苯	μg·L^-1	2005 [37]
		新霉素B	10 nmol·L^-1	2008 [38]
分子印迹法	分子印迹法	多巴胺	10 mmol·L^-1	2005 [40]
		人体血浆中抗生素丁胺卡那霉素	0.002 5 μg·mL^-1	2014 [41]
		卡那霉素	4.33×10^-8 mol·L^-1	2018 [42]
		尿酸	0.247 μg·mL^-1	2017 [43]
		组胺	25 ng·mL^-1	2015 [44]
		三聚氰胺	10^-9 mol·L^-1	2015
		对硫磷甲基(PM)	10^-13 mol·L^-1	2015 [45]
其他检测法		miRNA-93	1 fmol·L^-1	2017 [46]
		镉离子(Cd²⁺)	mg·L^-1~μg·L^-1	2015 [47]
		抗坏血酸	2×10^-5 mol·L^-1	2007 [49]

Table 1. Performance of different detection methods

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