The effect of mid-infrared supercontinnum generation in ZBLAN fibers is numerically investigated. Based on the finite element method, the influences of macroscopic bending on confinement loss, dispersion and nonlinearity of ZBLAN fibers with different numerical apertures are analyzed, and the bending cut- off wavelength of ZBLAN fibers is figured out. The evolution of mid- infrared supercontinuum generation in ZBLAN fibers is simulated by using the general nonlinear Schr?dinger’s equation. The results indicate that the drastic dropping of nonlinear coefficient in mid- infrared wavelength region suppresses the spectral broaden ? ing of ZBLAN fibers with low numerical aperture when no bending is applied. In the presence of bending, when the central frequency of the soliton approaches the boundary of bending-induced loss region, the soliton selffrequency shift effect is suppressed and the spectral broadening phenomenon is radicated as well.