At present, the space remote sensing camera still can not obtain the scene spectral radiance information in advance, so it can not adjust the exposure parameters according to the scene content. To this end, a method for adaptively configuring exposure parameters is proposed, which is realized by metering, calculating and imaging. In order to reduce the influence of metering camera on space remote sensing camera weight in practical application, the paper presents the application of a large-scale metering camera for metering, and a method of high resolution imaging based on low resolution image is proposed. Firstly, the change rule between the statistical characteristics of exposure of typical scenes and the scale. Large-scale metering image is used to conduct scale merging, and the exposure time of each scale is calculated. The function relationship between scale and exposure time is established by polynomial fitting, and the exposure parameters corresponding to the original scale are determined, so as to realize the imaging of space remote sensing camera with large-scale metering camera. According to the statistical results of unmanned aerial vehicle, the method can be applied to several typical scenes, the exposure parameter error between the value determined by large-scale fitting and the value determined by original scale image is less than 4%. Satellite picture data show that the error between the exposure parameters determined by large-scale fitting and the exposure parameters determined by the original scale image is less than 6% when the metering scale ratio is more than 90 times, but it still can accurately guide high-resolution camera imaging.