• Acta Optica Sinica
  • Vol. 40, Issue 9, 0910001 (2020)
Hong Jia, Chujun Zheng*, Canbiao Li, Wenbin Wang, and Yanbing Xu
Author Affiliations
  • School of Physics and Telecommunication Engineering, South China Normal University, Guangzhou, Guangdong 510006, China
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    DOI: 10.3788/AOS202040.0910001 Cite this Article Set citation alerts
    Hong Jia, Chujun Zheng, Canbiao Li, Wenbin Wang, Yanbing Xu. Retinal Blood Vessel Segmentation Based on Fuzzy C-Means Clustering According to the Local Line Structural Constraints[J]. Acta Optica Sinica, 2020, 40(9): 0910001 Copy Citation Text show less
    Flowchart of the proposed method
    Fig. 1. Flowchart of the proposed method
    Images of the pre-processing results. (a) Color fundus image; (b) green channel; (c) morphological open operation of Fig. 2(b); (d) image enhancement of Fig. 2(c) by CLAHE
    Fig. 2. Images of the pre-processing results. (a) Color fundus image; (b) green channel; (c) morphological open operation of Fig. 2(b); (d) image enhancement of Fig. 2(c) by CLAHE
    Multi-scale match filter response images. (a) Response image with σ=1; (b) response image with σ=2; (c) response image with all scales
    Fig. 3. Multi-scale match filter response images. (a) Response image with σ=1; (b) response image with σ=2; (c) response image with all scales
    Schematic diagram of B-COSFIRE. (a) Principle of B-COSFIRE; (b) symmetrical B-COSFIRE structure; (c) asymmetric B-COSFIRE structure
    Fig. 4. Schematic diagram of B-COSFIRE. (a) Principle of B-COSFIRE; (b) symmetrical B-COSFIRE structure; (c) asymmetric B-COSFIRE structure
    Response image of B-COSFIRE filtering. (a) Color fundus image; (b) result of B-COSFIRE filtering
    Fig. 5. Response image of B-COSFIRE filtering. (a) Color fundus image; (b) result of B-COSFIRE filtering
    Schematic diagram of line detector structure. (a) Line detector schematic diagram; (b) schematic diagram of line detector matched with vessel; (c) local neighborhood information
    Fig. 6. Schematic diagram of line detector structure. (a) Line detector schematic diagram; (b) schematic diagram of line detector matched with vessel; (c) local neighborhood information
    Segmentation result images of the DRIVE database. (a) The best result of images; (b) the worst result of images; (c) segmentation result of 15th images; (d) segmentation result of 18th images
    Fig. 7. Segmentation result images of the DRIVE database. (a) The best result of images; (b) the worst result of images; (c) segmentation result of 15th images; (d) segmentation result of 18th images
    Segmentation results of lesion image. (a) Segmentation result of K-means; (b) segmentation result of FCM; (c) segmentation result of proposed method
    Fig. 8. Segmentation results of lesion image. (a) Segmentation result of K-means; (b) segmentation result of FCM; (c) segmentation result of proposed method
    Results of proposed method and FCM. (a) Results of FCM; (b) results of the proposed method; (c) segmentation images manually marked by expert
    Fig. 9. Results of proposed method and FCM. (a) Results of FCM; (b) results of the proposed method; (c) segmentation images manually marked by expert
    MethodAccSenSpe
    FCM94.0460.7798.98
    FCM_LLC94.2167.2198.20
    Difference0.176.44-0.78
    Table 1. Segmentation performance comparison of proposed method and FCM%
    MethodAverage AccAverage SenAverage Spe
    The 2nd observer94.7377.6397.25
    Chaudhuri et al[7]92.8461.6897.41
    Zana and Klein[9]93.7769.71
    Azzopardi et al[17]94.2775.2697.07
    Meng et.al[21]93.8358.1193.11
    Kande et al[15]89.11
    Cai et al[22]93.0077.0095.00
    Wang et al[23]93.8256.8699.26
    Proposed method94.2167.2198.20
    Table 2. Performance of different retinal blood vessel segmentation methods%
    Hong Jia, Chujun Zheng, Canbiao Li, Wenbin Wang, Yanbing Xu. Retinal Blood Vessel Segmentation Based on Fuzzy C-Means Clustering According to the Local Line Structural Constraints[J]. Acta Optica Sinica, 2020, 40(9): 0910001
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