INTRACELLULAR MANIPULATION BY FEMTOSECOND LASERS: REVIEW

WATARU WATANABE; SACHIHIIRO MATSUNAGA; KIICHI FUKUI; KAZUYOSHI ITOH

Journals >Journal of Innovative Optical Health Sciences >Volume 2 >Issue 1 >Page 1 > Article

Journal of Innovative Optical Health Sciences
Vol. 2, Issue 1, 1 (2009)

INTRACELLULAR MANIPULATION BY FEMTOSECOND LASERS: REVIEW

WATARU WATANABE¹, SACHIHIIRO MATSUNAGA^2,*, KIICHI FUKUI², and KAZUYOSHI ITOH³

Author Affiliations

¹Photonics Research Institute National Institute of Advanced Industrial Science and Technology Midorigaoka, Ikeda, Osaka, Japan

²Department of Biotechnology, Graduate School of Engineering Osaka University, Yamadaoka, Suita, Osaka, Japan

³Department of Material and Life Science Graduate School of Engineering, Yamadaoka Suita, Osaka, Japan

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DOI: Cite this Article

WATARU WATANABE, SACHIHIIRO MATSUNAGA, KIICHI FUKUI, KAZUYOSHI ITOH. INTRACELLULAR MANIPULATION BY FEMTOSECOND LASERS: REVIEW[J]. Journal of Innovative Optical Health Sciences, 2009, 2(1): 1 Copy Citation Text

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Abstract

Multiphoton absorption of femtosecond laser pulses focused through an objective with high numerical aperture (NA) can be used to image and manipulate cellular and intracellular objects. This review highlights recent advances in intracellular manipulation, including nanosurgery and labeling in living cells with femtosecond lasers.

Keywords

ablation Femtosecond laser multiphoton microscopy nanosurgery photoconvertible fluorescent protein

WATARU WATANABE, SACHIHIIRO MATSUNAGA, KIICHI FUKUI, KAZUYOSHI ITOH. INTRACELLULAR MANIPULATION BY FEMTOSECOND LASERS: REVIEW[J]. Journal of Innovative Optical Health Sciences, 2009, 2(1): 1

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