The core of ecological restoration of territorial space is the holistic protection and systematic governance in the new period. It emphasizes the synergies between ecological conservation and socio-economic development. Landscape ecology focuses on the dynamics of landscape structure and function, and the interactive mechanism between them and human society from a comprehensive perspective, especially paying attention to processes coupling and spatial integration. The approach of "coupling patterns and processes-spatial and temporal scale-ecosystem services-landscape sustainability" in landscape ecology can provide significant disciplinary support for ecological restoration of territorial space. In the practice of ecological restoration of territorial space, pattern-process coupling theory should be employed to identify degraded or damaged life community of mountains, rivers, forests, farmlands, lakes and grasslands. Ecosystem services tradeoffs of multifunctional landscape for balancing social, economic and ecological demands are used to determine ecological restoration targets. For systematic restoration, the ecological security pattern is an effective way to optimize a multi-level restoration network, and the multi-scale cascade framework for human well-being safeguard can be built based on landscape sustainability.