In inertial confinement fusion (ICF) experimental studies, scientific-grade CCD coupled with streak camera is widely used in time and space diagnosis experiment with physical processes such as shock wave. As a significant property of the scientific grade CCD, nonlinearity plays an important role in experimental dealing. The experiment tests the nonlinearity property of the TEK 512×512DB CCD with the two schemes respectively: that the exposure time is fixed, the power density of the RS-5B is varied; power density is fixed, the exposure time is varied, and it shows the nonlinearity of the CCD is 0.595% and 0.508% respectively, meanwhile, the two experimental scheme are evaluated by analyzing kinds of factors, indicating that the first scheme is better, which provides the reference for establishment of automated testing platform.