China is a world leader in automobile production, and its production and sales has ranked first in the world for nine consecutive years. However, research on the automobile industry is more concentrated on the regional scale, and research on the urban scale is relatively rare. This paper takes Liuzhou City as a case, and analyzes the spatial distribution and influencing factors of Liuzhou automobile manufacturing enterprises by using micro-enterprise data, nuclear density estimation and negative binomial regression model. The results show that: (1) The automobile manufacturing enterprises are mainly concentrated in Hexi, Luowei, Hedong and Yanghe groups in Liuzhou City. The scope of corporate agglomeration gradually spreads to the east and west sides. The eastward diffusion is mainly in Liudong new district and the westward diffusion is mainly in the Hexihigh-tech industrial development area in Liuzhou City. (2) The automobile manufacturing enterprises in Liuzhou City have a significant agglomeration in the spatial distribution within the range of 0~11 km, and the intensity of spatial agglomeration first increases and then decreases. (3) Land price and traffic conditions, localization economy and policy factors have significant impacts on the spatial distribution of automobile manufacturing enterprises in Liuzhou City. At the same Time, JIT (Just in Time) production mode of automobile manufacturing also has an important influence. On this basis, the circular accumulation mechanism, location proximity mechanism and price transmission mechanism of location selection and spatial distribution of automobile manufacturing enterprises are proposed.