We proposed a periodic mid-infrared broadband chiral structure. Its unit cell consists of four indium tin oxide (ITO) helix subunits with different radii. The simulation results show that the flat-topped broadband circular dichroism (CD) can be achieved in the mid-infrared band by optimizing the parameters of helix structures. The simulation results also show that compared with the metallic (Ag and Au) helix structures, the ITO helix structure proposed exhibits evidently better broadband CD and optical activity, which provides a new idea for the design of broadband polarization state control devices in the mid-infrared band.